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Identification of growth years of Hengshan imitative wild culture Astragali Radix and investigation into the accumulation rules of flavonoids and saponins
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Si-yun GAO1, 3, 4, Ke LI1, 3, 4, *, Yi-feng XIONG1, 2, 3, 4, Xue-mei QIN1, 3, 4, *, Gui-mei CUI5, Xiang ZHANG6, Guan-hua DU7
Acta Pharmaceutica Sinica | 2018, 53(1) : 147 - 154
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Acta Pharmaceutica Sinica | 2018, 53(1): 147-154
• ORIGINAL ARTICLES •
Identification of growth years of Hengshan imitative wild culture Astragali Radix and investigation into the accumulation rules of flavonoids and saponins
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Si-yun GAO1, 3, 4, Ke LI1, 3, 4, *, Yi-feng XIONG1, 2, 3, 4, Xue-mei QIN1, 3, 4, *, Gui-mei CUI5, Xiang ZHANG6, Guan-hua DU7
Affiliations
  • 1. Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China
  • 2. Colleage of Chemrtry and Chemical Engineering, Shanxi University, Taiyuan 030006, China
  • 3. The Efficacy of Chinese Medicine Material and New Drug Key Lab of Shanxi Provience, Shanxi University, Taiyuan 030006, China
  • 4. Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030006, China
  • 5. Biotechnology Research Certer, Shanxi Academy of Agriculture Science, Taiyuan 030031, China
  • 6. Medical College, University of Louisville, Louisville 40292, American
  • 7. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2018-01-12 doi: 10.16438/j.0513-4870.2017-0883
Outline
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Currently, the specification grading standard for Astragali Radix can not accurately reflect growth years. The aim of this study is to identify the growth ring number of different parts of 1 to 6 year Hengshan imitative wild culture Astragali Radix, in order to get a different absolute growth years, to classify the accumulation rules of the content of flavonoids and saponins, and to lay the foundation for evaluating quality of Astragali Radix. Observing growth ring numbers of 1-6 years Astragali Radix by means of hand sections and paraffin sections in the study, and analyzing the number of different growth years and different diameter. At the same time, HPLC-UV-ELSD was used to analyze the 12 index components of the samples with absolute growth years of 2 to 6 years. The results indicated that the growth ring number excepting hollow part is consistent with the actual growth period of Astragali Radix and the number of growth rings gradually decreased from the upper to lower. The results of HPLC-UV-ELSD determination showed that the saponins content of 3-year-old Astragali Radix was the highest while the flavonoids content of the 4-year-old reached the maximum. The study provided the basis for foundation of the specification grading standard for Astragali Radix and clinical rational use drug.

Astragali Radix  /  growth ring  /  diameter  /  age identification  /  grading classification  /  index component
Si-yun GAO, Ke LI, Yi-feng XIONG, Xue-mei QIN, Gui-mei CUI, Xiang ZHANG, Guan-hua DU. Identification of growth years of Hengshan imitative wild culture Astragali Radix and investigation into the accumulation rules of flavonoids and saponins[J]. Acta Pharmaceutica Sinica, 2018 , 53 (1) : 147 -154 . DOI: 10.16438/j.0513-4870.2017-0883
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Article Info
doi: 10.16438/j.0513-4870.2017-0883
  • Receive Date：2017-09-07
  • Online Date：2026-01-15
  • Published：2018-01-12
Article Data
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History
  • Received：2017-09-07
  • Revised：2017-10-10
Funding
Affiliations
    1. Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China
    2. Colleage of Chemrtry and Chemical Engineering, Shanxi University, Taiyuan 030006, China
    3. The Efficacy of Chinese Medicine Material and New Drug Key Lab of Shanxi Provience, Shanxi University, Taiyuan 030006, China
    4. Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030006, China
    5. Biotechnology Research Certer, Shanxi Academy of Agriculture Science, Taiyuan 030031, China
    6. Medical College, University of Louisville, Louisville 40292, American
    7. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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