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Advances in study of pharmacological effects of ginsenoside Rg1 in hepatic diseases
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Piao LUO1, 2, Shi-feng CHU1, 2, Yan GAO2, Lin-ming LUO1, Lan PENG1, Nai-hong CHEN1, 2, *
Acta Pharmaceutica Sinica | 2018, 53(1) : 21 - 27
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Acta Pharmaceutica Sinica | 2018, 53(1): 21-27
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Advances in study of pharmacological effects of ginsenoside Rg1 in hepatic diseases
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Piao LUO1, 2, Shi-feng CHU1, 2, Yan GAO2, Lin-ming LUO1, Lan PENG1, Nai-hong CHEN1, 2, *
Affiliations
  • 1. College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
  • 2. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2018-01-12 doi: 10.16438/j.0513-4870.2017-0578
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Ginsenoside Rg1 is one of the main active components of ginseng with various pharmacological activities including anti-inflammatory, anti-oxidation, anti-aging, anti-tumor and anti-apoptosis. Ginsenoside Rg1 plays a protective role in multiple tissues and organs, which shows the multiple targeting properties of the pharmacological effects. Recently, a number of studies have demonstrated that ginsenoside Rg1 has a protective role in the liver due to its multiple pharmacological effects. In chemical liver injury models, or in other liver injury models, ginsenoside Rg1 can alleviate liver necrosis induced by oxidative stress and inflam-mation. This article provides a review of the recent studies on the efficacy of ginsenoside Rg1 in the treatment of various liver damage and the molecular mechanism.

liver injury  /  ginsenoside Rg1  /  oxidative stress  /  anti-inflammatory  /  anti-apoptosis
Piao LUO, Shi-feng CHU, Yan GAO, Lin-ming LUO, Lan PENG, Nai-hong CHEN. Advances in study of pharmacological effects of ginsenoside Rg1 in hepatic diseases[J]. Acta Pharmaceutica Sinica, 2018 , 53 (1) : 21 -27 . DOI: 10.16438/j.0513-4870.2017-0578
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Article Info
doi: 10.16438/j.0513-4870.2017-0578
  • Receive Date：2017-06-19
  • Online Date：2026-01-15
  • Published：2018-01-12
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History
  • Received：2017-06-19
  • Revised：2017-09-03
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Affiliations
    1. College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
    2. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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