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A novel sesquiterpenoid from Curcuma longa L.
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Bo-yu LI1, 2, Cheng PENG1, Hong-zhen SHU1, 2, Fei LIU1, 2, *, Liang XIONG1, 2, *
Acta Pharmaceutica Sinica | 2022, 57(12) : 3603 - 3607
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Acta Pharmaceutica Sinica | 2022, 57(12): 3603-3607
• Original Articles •
A novel sesquiterpenoid from Curcuma longa L.
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Bo-yu LI1, 2, Cheng PENG1, Hong-zhen SHU1, 2, Fei LIU1, 2, *, Liang XIONG1, 2, *
Affiliations
  • 1. State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
  • 2. Institute of Innovative Medicine Ingredients of Southwest Specialty Medicinal Materials, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
Published: 2022-12-12 doi: 10.16438/j.0513-4870.2022-0702
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A new compound was isolated from the 95% ethanolic extract of the rhizomes of Curcuma longa L. using silica gel column chromatography, medium pressure liquid chromatography, and semi-preparative high performance liquid chromatography. The structure and absolute configuration of the compound was elucidated by HR-ESI-MS, NMR, and electronic circular dichroism (ECD) calculations. It is a novel sesquiterpenoid, which is named as isoturmeronol B (1). The carbon skeleton of compound 1 is similar to that of bisabolane-type sesquiterpenoid. The only difference is that the methyl group at C-4 in bisabolene-type sesquiterpenoid is migrated to C-5 in compound 1. Besides, the anti-inflammatory and antioxidant activities of the compound 1 were evaluated. The results showed that 1 has no anti-inflammatory and antioxidant activities.

Curcuma longa L.  /  isolation and identification  /  new compound  /  absolute configuration  /  sesquiterpenoid
Bo-yu LI, Cheng PENG, Hong-zhen SHU, Fei LIU, Liang XIONG. A novel sesquiterpenoid from Curcuma longa L.[J]. Acta Pharmaceutica Sinica, 2022 , 57 (12) : 3603 -3607 . DOI: 10.16438/j.0513-4870.2022-0702
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Article Info
doi: 10.16438/j.0513-4870.2022-0702
  • Receive Date：2022-06-07
  • Online Date：2025-12-24
  • Published：2022-12-12
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History
  • Received：2022-06-07
  • Revised：2022-06-23
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Affiliations
    1. State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
    2. Institute of Innovative Medicine Ingredients of Southwest Specialty Medicinal Materials, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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