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A new polycyclic polyprenylated acylphloroglucinol from Hypericum pseudohenryi
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Yong-hui MA1, 2, Hao-ran SUN2, Jin LI1, *, Teng-fei JI2, 3, *
Acta Pharmaceutica Sinica | 2022, 57(12) : 3596 - 3602
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Acta Pharmaceutica Sinica | 2022, 57(12): 3596-3602
Original Articles
A new polycyclic polyprenylated acylphloroglucinol from Hypericum pseudohenryi
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Yong-hui MA1, 2, Hao-ran SUN2, Jin LI1, *, Teng-fei JI2, 3, *
Affiliations
  • 1. Xinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, Key Laboratory of Plant Stress Biology in Arid Land, College of Life Science, Xinjiang Normal University, Urumqi 830054, China
  • 2. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China
  • 3. Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810001, China
Published: 2022-12-12 doi: 10.16438/j.0513-4870.2022-0654
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Eight polycyclic polyprenylated acylphloroglucinols (PPAPs) were isolated from the 95% ethanol extract of Hypericum pseudohenryi by MCI column, silica gel column and preparative HPLC. These compounds were defined as hypseudohenrin L (1), hyperbeanin P (2), furohyperforin (3), furoadhyperforin (4), ascyronone F (5), attenuatumione E (6), hyphenrone T (7) and hyperforatone N (8), compound 1 is a new compound. Compounds 1, 3, 5, 7 showed an inhibitory effect on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in macrophage cells.

Hypericum pseudohenryi  /  polycyclic polyprenylated acylphloroglucinol  /  nitric oxide  /  anti-inflammatoy activity
Yong-hui MA, Hao-ran SUN, Jin LI, Teng-fei JI. A new polycyclic polyprenylated acylphloroglucinol from Hypericum pseudohenryi[J]. Acta Pharmaceutica Sinica, 2022 , 57 (12) : 3596 -3602 . DOI: 10.16438/j.0513-4870.2022-0654
Year 2022 volume 57 Issue 12
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Article Info
doi: 10.16438/j.0513-4870.2022-0654
  • Receive Date:2022-05-27
  • Online Date:2025-12-24
  • Published:2022-12-12
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History
  • Received:2022-05-27
  • Revised:2022-06-10
Funding
Affiliations
    1. Xinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, Key Laboratory of Plant Stress Biology in Arid Land, College of Life Science, Xinjiang Normal University, Urumqi 830054, China
    2. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China
    3. Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810001, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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