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A new patchoulane-type sesquiterpenoid from patchouli oil and its anti-inflammatory activity
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Tian-hao ZHANG1, 2, Cheng PENG1, 2, Jing ZUO1, 2, Qi ZHENG1, 2, Chun-wang MENG1, 2, Li GUO1, 2, Qin-mei ZHOU1, 2, 3, *, Liang XIONG1, 2, *
Acta Pharmaceutica Sinica | 2022, 57(10) : 3163 - 3167
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Acta Pharmaceutica Sinica | 2022, 57(10): 3163-3167
Original Articles
A new patchoulane-type sesquiterpenoid from patchouli oil and its anti-inflammatory activity
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Tian-hao ZHANG1, 2, Cheng PENG1, 2, Jing ZUO1, 2, Qi ZHENG1, 2, Chun-wang MENG1, 2, Li GUO1, 2, Qin-mei ZHOU1, 2, 3, *, Liang XIONG1, 2, *
Affiliations
  • 1. State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
  • 2. Institute of Innovative Medicine Ingredients of Southwest Specialty Medicinal Materials, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
  • 3. Innovation Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
Published: 2022-10-12 doi: 10.16438/j.0513-4870.2022-0514
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A new [7, 10∶1, 5]-patchoulane-type sesquiterpenoid was isolated and purified by silica gel column chromatography, medium pressure liquid chromatography, and semi-preparative high performance liquid chromatography. Based on IR, HR-ESI-MS, NMR, and X-single crystal diffraction data analyses, compound 1 was determined to be (-)-(3S, 4R, 5R, 7R, 10R)-[7, 10∶1, 5]patchoul-1(2)-en-3, 4-diol. It showed an inhibitory effect on LPS-induced NO production in RAW264.7 cells.

patchouli oil  /  patchoulane type  /  sesquiterpenoid  /  anti-inflammation  /  RAW264.7 cell
Tian-hao ZHANG, Cheng PENG, Jing ZUO, Qi ZHENG, Chun-wang MENG, Li GUO, Qin-mei ZHOU, Liang XIONG. A new patchoulane-type sesquiterpenoid from patchouli oil and its anti-inflammatory activity[J]. Acta Pharmaceutica Sinica, 2022 , 57 (10) : 3163 -3167 . DOI: 10.16438/j.0513-4870.2022-0514
Year 2022 volume 57 Issue 10
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Article Info
doi: 10.16438/j.0513-4870.2022-0514
  • Receive Date:2022-04-28
  • Online Date:2025-12-24
  • Published:2022-10-12
Article Data
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History
  • Received:2022-04-28
  • Revised:2022-05-24
Funding
Affiliations
    1. State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
    2. Institute of Innovative Medicine Ingredients of Southwest Specialty Medicinal Materials, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
    3. Innovation Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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