Home Journals Articles Updates About
CN
image
收藏切换
Identification of potential Q-markers of Semen Armeniacae Amarum based on UPLC-MS/MS and metabonomics
收藏切换
PDF
Yao CHENG1, Yue-lin BI2, Xin FENG2, Jia-qi WANG2, Hao-ran XU2, Tong-hua ZHANG2, Geng-yuan YU2, Chen-ning ZHANG2, Jing-hong WANG1, *, Yi-kun SUN2, *
Acta Pharmaceutica Sinica | 2022, 57(10) : 3195 - 3202
Less
收藏切换
Acta Pharmaceutica Sinica | 2022, 57(10): 3195-3202
• Original Articles •
Identification of potential Q-markers of Semen Armeniacae Amarum based on UPLC-MS/MS and metabonomics
Full
Yao CHENG1, Yue-lin BI2, Xin FENG2, Jia-qi WANG2, Hao-ran XU2, Tong-hua ZHANG2, Geng-yuan YU2, Chen-ning ZHANG2, Jing-hong WANG1, *, Yi-kun SUN2, *
Affiliations
  • 1. Department of Pharmacy, Wangjing Hospital, Chinese Academy of Traditional Chinese Medicine, Beijing 100102, China
  • 2. College of Traditional Chinese Medicine, Beijing University of Traditional Chinese Medicine, Beijing 102488, China
Published: 2022-10-12 doi: 10.16438/j.0513-4870.2022-0581
Outline
收藏切换

Bitter almonds (Semen Armeniacae Amarum) are prone to oil deterioration during storage, so they often require mashing prior to clinical use. To confirm the medical value of bitter almonds "being mashed when used" and to determine the optimal storage conditions for bitter almonds, UPLC-MS/MS was used to perform a comparative study of the chemical composition of bitter almonds in different storage states (mashed and unmashed), storage times (0, 2 and 4 weeks), and storage temperatures (25 ℃ and 4 ℃). A total of 58 substances were identified in bitter almond extracts through literature review, this group's previous work, and a Compound Discoverer software search. Statistically significant differences were found in the chemical composition and content of bitter almonds in different storage states, storage times, and storage temperatures. The results show that the chemical composition of bitter almonds stored unmashed was more stable than that of bitter almonds stored mashed; the chemical composition of bitter almonds stored at 4 ℃ was more stable than that of bitter almonds stored at 25 ℃; and the shorter the storage time, the less the chemical composition changed. Amygdalin, the main medicinal component of bitter almonds, showed statistically significant differences in content under the above three storage conditions, which can be used as a potential quality marker for bitter almonds.

Semen Armeniacae Amarum  /  mashed when used  /  UPLC-MS/MS  /  differential compound  /  metabolomics
Yao CHENG, Yue-lin BI, Xin FENG, Jia-qi WANG, Hao-ran XU, Tong-hua ZHANG, Geng-yuan YU, Chen-ning ZHANG, Jing-hong WANG, Yi-kun SUN. Identification of potential Q-markers of Semen Armeniacae Amarum based on UPLC-MS/MS and metabonomics[J]. Acta Pharmaceutica Sinica, 2022 , 57 (10) : 3195 -3202 . DOI: 10.16438/j.0513-4870.2022-0581
Appendix
Less
Year 2022 volume 57 Issue 10
PDF
113
46
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2022-0581
  • Receive Date：2022-05-12
  • Online Date：2025-12-24
  • Published：2022-10-12
Article Data
Affiliations
History
  • Received：2022-05-12
  • Revised：2022-08-02
Funding
Affiliations
    1. Department of Pharmacy, Wangjing Hospital, Chinese Academy of Traditional Chinese Medicine, Beijing 100102, China
    2. College of Traditional Chinese Medicine, Beijing University of Traditional Chinese Medicine, Beijing 102488, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2022-0581
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House