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Study on the chemical constituents of the fruits of Psidium guajava
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Yue YU, Xing-yan SUN, Kai-ling XU, Chuang-jun LI, Jin-hua WANG, Dong-ming ZHANG*
Acta Pharmaceutica Sinica | 2022, 57(8) : 2416 - 2422
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Acta Pharmaceutica Sinica | 2022, 57(8): 2416-2422
Original Articles
Study on the chemical constituents of the fruits of Psidium guajava
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Yue YU, Xing-yan SUN, Kai-ling XU, Chuang-jun LI, Jin-hua WANG, Dong-ming ZHANG*
Affiliations
  • Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2022-08-12 doi: 10.16438/j.0513-4870.2022-0285
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Psidium guajava Linn. is an evergreen shrub or small tree of Psidium Linnaeus in the Myrtaceae family. One new glycoside (1) together with 3 known meroterpenoids (2-4) and 9 known glycosides (5-13) were isolated from the fruits of Psidium guajava Linn.. The structure of the new compound was elucidated by the spectroscopic data analysis of HR-ESIMS, 1D- and 2D-NMR, and it was named psiguaoside A (1). The known compounds were identified as guajadial (2), 4, 5-diepipsidial A (3), psidial A (4), chrysin-8-C-β-D-glucoside (5), 2, 6-dihydroxy-3, 5-dimethyl-4-O-β-D-glucopyranosyl-benzophenone (6), quercetin-3-O-β-D-glucopyranoside (7), quercetin-3-O-xyloside (8), guaijaverin (9), avicularin (10), guavinoside E (11), guavinoside B (12), guajaphenone A (13). In the bioactivity assay, compound 3 exhibited significant inhibitory activitiy of U87 with IC50 values of 8.379 μmol·L-1.

Psidium guajava  /  fruit  /  chemical constituent  /  meroterpenoid  /  anti-tumor
Yue YU, Xing-yan SUN, Kai-ling XU, Chuang-jun LI, Jin-hua WANG, Dong-ming ZHANG. Study on the chemical constituents of the fruits of Psidium guajava[J]. Acta Pharmaceutica Sinica, 2022 , 57 (8) : 2416 -2422 . DOI: 10.16438/j.0513-4870.2022-0285
Year 2022 volume 57 Issue 8
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doi: 10.16438/j.0513-4870.2022-0285
  • Receive Date:2022-03-04
  • Online Date:2025-12-23
  • Published:2022-08-12
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  • Received:2022-03-04
  • Revised:2022-03-21
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    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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