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Research on the antioxidant activity of metabolites from a sponge-derived fungus Alternaria sp. F49
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Yu-shi CHEN, Jia-rong LENG, Shu-ting LIN, Shao-yun WANG, Yong-qi TIAN*
Acta Pharmaceutica Sinica | 2022, 57(7) : 2120 - 2125
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Acta Pharmaceutica Sinica | 2022, 57(7): 2120-2125
Original Articles
Research on the antioxidant activity of metabolites from a sponge-derived fungus Alternaria sp. F49
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Yu-shi CHEN, Jia-rong LENG, Shu-ting LIN, Shao-yun WANG, Yong-qi TIAN*
Affiliations
  • College of Biological Science and Engineering, Fuzhou University, Fuzhou 350108, China
Published: 2022-07-12 doi: 10.16438/j.0513-4870.2021-1868
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To study the chemical constituents from the the deep-sea fungus Alternaria sp. F49. Seven compounds were isolated from the EtOAc extract by using silica gel, Sephadex LH-20, ODS and HPLC methods. Based on the spectroscopic analysis, their structures were identified as (8R)-5-O-methyl-orcinotriol (1), orcinotriol (2), α-acetylorcinol (3), 3'-hydroxyalternariol 5-O-methyl ether (4), altenusiol (5), altenusin (6), and 5'-methoxy-6-methyl-biphenyl-3, 4, 3'-triol (7). (8R)-5-O-Methyl-orcinotriol (1) is a new phenolic compound which has never been reported in the literature. Compounds 4-7 showed strong DPPH free radical scavenging activity; whereas compounds 1-7 showed strong ABTS free radical scavenging activity.

sponge-derived fungus  /  Alternaria sp. F49  /  secondary metabolite  /  DPPH free radical scavenging activity  /  ABTS free radical scavenging activity
Yu-shi CHEN, Jia-rong LENG, Shu-ting LIN, Shao-yun WANG, Yong-qi TIAN. Research on the antioxidant activity of metabolites from a sponge-derived fungus Alternaria sp. F49[J]. Acta Pharmaceutica Sinica, 2022 , 57 (7) : 2120 -2125 . DOI: 10.16438/j.0513-4870.2021-1868
Year 2022 volume 57 Issue 7
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doi: 10.16438/j.0513-4870.2021-1868
  • Receive Date:2021-12-31
  • Online Date:2025-12-23
  • Published:2022-07-12
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  • Received:2021-12-31
  • Revised:2022-01-27
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    College of Biological Science and Engineering, Fuzhou University, Fuzhou 350108, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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