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Research advances of photosensitizer in photodynamic therapy of glioblastoma
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Hong-cheng ZHAO, Yue-qing WANG, Qing-yun LI, Hao DENG, Xiao TAN*, Xiao-wen LIU*
Acta Pharmaceutica Sinica | 2022, 57(6) : 1750 - 1757
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Acta Pharmaceutica Sinica | 2022, 57(6): 1750-1757
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Research advances of photosensitizer in photodynamic therapy of glioblastoma
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Hong-cheng ZHAO, Yue-qing WANG, Qing-yun LI, Hao DENG, Xiao TAN*, Xiao-wen LIU*
Affiliations
  • Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Medical College of China Three Gorges University, Yichang 443003, China
Published: 2022-06-12 doi: 10.16438/j.0513-4870.2021-1248
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Glioblastoma is a malignant tumor in central nervous system, which has strong invasion, poor prognosis and short survival time. At present, the main treatment strategy of glioblastoma is surgical excision, supplemented by radiotherapy and chemotherapy. However, due to incomplete resection and high recurrence rate, it is urgent to find novel therapeutic method for glioblastoma. Photodynamic therapy, as a promising non-surgical treatment, provides a new strategy for postoperative adjuvant therapy of glioblastoma. This review summarizes the mechanism and clinical application of photodynamic therapy mediated by various photosensitizers in glioblastoma, in order to provide help for the treatment of glioblastoma.

photosensitizer  /  glioblastoma  /  photodynamic therapy  /  adjuvant therapy  /  clinical application
Hong-cheng ZHAO, Yue-qing WANG, Qing-yun LI, Hao DENG, Xiao TAN, Xiao-wen LIU. Research advances of photosensitizer in photodynamic therapy of glioblastoma[J]. Acta Pharmaceutica Sinica, 2022 , 57 (6) : 1750 -1757 . DOI: 10.16438/j.0513-4870.2021-1248
Year 2022 volume 57 Issue 6
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doi: 10.16438/j.0513-4870.2021-1248
  • Receive Date:2021-08-30
  • Online Date:2025-12-23
  • Published:2022-06-12
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  • Received:2021-08-30
  • Revised:2021-10-12
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    Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Medical College of China Three Gorges University, Yichang 443003, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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