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Two new compounds from Smilax glabra Roxb.
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Cai-ying PENG, Shuang CHENG, Yan-fen XIONG, Jian-qun LIU, Hui-lian HUANG, Ji-cheng SHU*
Acta Pharmaceutica Sinica | 2022, 57(6) : 1855 - 1862
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Acta Pharmaceutica Sinica | 2022, 57(6): 1855-1862
• Original Articles •
Two new compounds from Smilax glabra Roxb.
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Cai-ying PENG, Shuang CHENG, Yan-fen XIONG, Jian-qun LIU, Hui-lian HUANG, Ji-cheng SHU*
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  • Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China
Published: 2022-06-12 doi: 10.16438/j.0513-4870.2021-1646
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Twenty compounds were isolated from the ethyl acetate extract of Smilax glabra by using various chromatographic techniques, including macroreticular resin, silica gel, Sephadex LH-20 and semi-preparative HPLC. Their structures were elucidated by physicochemical properties, MS and spectroscopic data. These compounds were elucidated as glabraside A (1), glabraone A (2), 5-hydroxy-3ʹ, 4ʹ, 7-trimethoxy-flavanone (3), naringenin (4), quercetin 7-O-α-L-rhamnoside (5), neoastilbin (6), neoisoastilbin (7), isoastilbin (8), eriodictyol-7-O-β-D-glucopyranoside (9), naringenin-7-O-α-L-rhamnoside (10), kaempferol 3-O-[4′′′′′-O-acetyl-α-L-rhamnosyl-(1→6)]-[β-D-glucopyranosyl-(1→2)]-β-D-glucopyranoside (11), 5-hydroxymaltol (12), 3, 4, 5-trimethoxyphenyl-1-O-β-D-glucopyranoside (13), 2-(3′, 4′-dihydroxyphenyl)-1, 3-benzodioxole-5-aldehyde (14), kompasinol A (15), (+)-syringaresinol (16), cis-resveratrol (17), trans-resveratrol (18), flufuran (19) and 5-hydroxymethyl-furaldehyde (20). Two new compounds (1 and 2) showed inhibitory activity toward nitric oxide (NO) production, with IC50 values of 56.8 and 29.5 μmol·L-1, respectively.

Smilax glabra  /  chemical constituent  /  glabraside A  /  glabraone A  /  anti-inflammatory activity
Cai-ying PENG, Shuang CHENG, Yan-fen XIONG, Jian-qun LIU, Hui-lian HUANG, Ji-cheng SHU. Two new compounds from Smilax glabra Roxb.[J]. Acta Pharmaceutica Sinica, 2022 , 57 (6) : 1855 -1862 . DOI: 10.16438/j.0513-4870.2021-1646
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Year 2022 volume 57 Issue 6
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Article Info
doi: 10.16438/j.0513-4870.2021-1646
  • Receive Date：2021-11-18
  • Online Date：2025-12-23
  • Published：2022-06-12
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  • Received：2021-11-18
  • Revised：2021-12-28
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    Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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