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The research progress on the structure pharmaceutics and dosage form structures of traditional Chinese medicines
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Ting YANG1, 2, 3, Zhe LI2, Dao-ming FENG1, 2, Ying ZHANG1, Jing LI1, Hui-peng XU1, Wen-ting WU2, Li WU1, 2, Xian-zhen YIN1, 2, Wei-feng ZHU2, *, Ji-wen ZHANG1, 2, 3, *
Acta Pharmaceutica Sinica | 2021, 56(8) : 2070 - 2085
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Acta Pharmaceutica Sinica | 2021, 56(8): 2070-2085
• Special Reports: Structural Chinese Medicine •
The research progress on the structure pharmaceutics and dosage form structures of traditional Chinese medicines
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Ting YANG1, 2, 3, Zhe LI2, Dao-ming FENG1, 2, Ying ZHANG1, Jing LI1, Hui-peng XU1, Wen-ting WU2, Li WU1, 2, Xian-zhen YIN1, 2, Wei-feng ZHU2, *, Ji-wen ZHANG1, 2, 3, *
Affiliations
  • 1. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
  • 2. Jiangxi University of Chinese Medicine, Nanchang 330004, China
  • 3. Nanjing University of Chinese Medicine, Nanjing 210023, China
Published: 2021-08-12 doi: 10.16438/j.0513-4870.2021-0912
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Traditional Chinese medicine (TCM) preparations have made tremendous progresses in modernization, whereas there exist relatively few researches pertaining to preparation structures. As demonstrated by the theory and practice of structure pharmaceutics, the structure properties of dosage forms have significant influences on the quality and efficacy of drugs, which might offer reference for the research and development of TCM dosage forms. With the application of synchrotron radiation X-ray micro-computed tomography (SR-μCT) and other novel technologies in recent years, researches in structure pharmaceutics have made huge advancement, which provide reference and methodology basis for the study of TCM preparations. The article generalized and summarized the recent progresses and methods in the structure researches of pharmaceutics and TCM preparations, and further explored the significance of the researches of structure of TCM preparations. It is expected to provide the basis for the dosage form design, production process improvement, and quality evaluation of TCM and promote the modernization of TCM preparations.

structure pharmaceutics  /  traditional Chinese medicine preparation  /  imaging  /  three dimension  /  quality evaluation
Ting YANG, Zhe LI, Dao-ming FENG, Ying ZHANG, Jing LI, Hui-peng XU, Wen-ting WU, Li WU, Xian-zhen YIN, Wei-feng ZHU, Ji-wen ZHANG. The research progress on the structure pharmaceutics and dosage form structures of traditional Chinese medicines[J]. Acta Pharmaceutica Sinica, 2021 , 56 (8) : 2070 -2085 . DOI: 10.16438/j.0513-4870.2021-0912
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Article Info
doi: 10.16438/j.0513-4870.2021-0912
  • Receive Date：2021-06-22
  • Online Date：2025-12-18
  • Published：2021-08-12
Article Data
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History
  • Received：2021-06-22
  • Revised：2021-07-06
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Affiliations
    1. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
    2. Jiangxi University of Chinese Medicine, Nanchang 330004, China
    3. Nanjing University of Chinese Medicine, Nanjing 210023, China
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表12种不同金属材料的力学参数
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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