Home Journals Articles Updates About
CN
image
收藏切换
Desorption electrospray ionization-mass spectrometry in the analysis of natural medicines
收藏切换
PDF
Long-chan LIU1, Yi-fan LI1, Fang-li ZHANG1, Lin-nan LI1, *, Zheng-tao WANG1, 2, Li YANG1, 2, *
Acta Pharmaceutica Sinica | 2021, 56(8) : 2204 - 2216
Less
收藏切换
Acta Pharmaceutica Sinica | 2021, 56(8): 2204-2216
• Reviews •
Desorption electrospray ionization-mass spectrometry in the analysis of natural medicines
Full
Long-chan LIU1, Yi-fan LI1, Fang-li ZHANG1, Lin-nan LI1, *, Zheng-tao WANG1, 2, Li YANG1, 2, *
Affiliations
  • 1. The MOE Key Laboratory of Standardization of Chinese Medicines and the SATCM Key Laboratory of New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
  • 2. Shanghai R&D Center for Standardization of Chinese Medicines, Shanghai 201203, China
Published: 2021-08-12 doi: 10.16438/j.0513-4870.2021-0204
Outline
收藏切换

Desorption electrospray ionization mass spectrometry (DESI-MS) is a newly emerging in-situ ionization mass spectrometry analysis technology. The ionization process occurs in an open ambient environment at atmospheric pressure, and has the characteristics of simple sample pretreatment, quick and sensitive analysis, and is widely used in biomedicine, pharmaceutical analysis, food safety, environmental monitoring, and material characterization. Natural medicines, such as Chinese herbal medicines, contain a variety of chemical components. Extraction, separation, identification, and in vitro and in vivo efficacy evaluation of natural medicines, especially research on active ingredients with significant efficacy, have received long-term attention. The development of DESI-MS technology provides many new opportunities for direct and rapid analysis of active ingredients in natural medicines. This article briefly introduces the principles, characteristics, influencing factors, and technical progress of DESI-MS technology, and systematically summarizes progress in the research and application of this technology to natural medicines such as Chinese herbal medicines and other plant samples with pharmacological activity. The future application prospects in this field are further presented.

desorption electrospray ionization-mass spectrometry  /  Chinese herbal medicine  /  natural medicine  /  imaging mass spectrometry  /  quality control
Long-chan LIU, Yi-fan LI, Fang-li ZHANG, Lin-nan LI, Zheng-tao WANG, Li YANG. Desorption electrospray ionization-mass spectrometry in the analysis of natural medicines[J]. Acta Pharmaceutica Sinica, 2021 , 56 (8) : 2204 -2216 . DOI: 10.16438/j.0513-4870.2021-0204
Appendix
Less
Year 2021 volume 56 Issue 8
PDF
165
65
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2021-0204
  • Receive Date：2021-02-02
  • Online Date：2025-12-18
  • Published：2021-08-12
Article Data
Affiliations
History
  • Received：2021-02-02
  • Revised：2021-04-14
Funding
Affiliations
    1. The MOE Key Laboratory of Standardization of Chinese Medicines and the SATCM Key Laboratory of New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    2. Shanghai R&D Center for Standardization of Chinese Medicines, Shanghai 201203, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2021-0204
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House