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Lipid metabolism and hematological malignancies
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Yi-chen LIU, Ting-ting DU, Qing-hua WANG, Zhi-hui ZHANG, Xiao-guang CHEN*
Acta Pharmaceutica Sinica | 2021, 56(9) : 2456 - 2463
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Acta Pharmaceutica Sinica | 2021, 56(9): 2456-2463
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Lipid metabolism and hematological malignancies
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Yi-chen LIU, Ting-ting DU, Qing-hua WANG, Zhi-hui ZHANG, Xiao-guang CHEN*
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  • State Key Laboratory of Bioactive Substance and Function of National Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2021-09-12 doi: 10.16438/j.0513-4870.2021-0030
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With the deepening of research in recent years, tumor metabolic reprogramming has gradually become the focus of research, and targeting tumor cell metabolism has also become a new means of tumor therapy. The metabolic process affects almost all the physiological processes of the organism, and lipid metabolism is an important part of the metabolic process. Studies have shown that changes in lipid uptake, storage and fatty acid synthesis and decomposition have occurred in a variety of tumors. Abnormal lipid metabolism will promote the rapid proliferation of tumors. Abnormal expression of a variety of key metabolic enzymes in the process of lipid metabolism is the key to tumor progression. The purpose of this paper is to explain the metabolic regulation of lipid metabolism and related metabolic enzymes in hematological tumors, and to provide ideas for the treatment of hematological tumors.

lipid metabolism  /  fatty acid oxidation  /  metabolic enzyme  /  hematological malignancy
Yi-chen LIU, Ting-ting DU, Qing-hua WANG, Zhi-hui ZHANG, Xiao-guang CHEN. Lipid metabolism and hematological malignancies[J]. Acta Pharmaceutica Sinica, 2021 , 56 (9) : 2456 -2463 . DOI: 10.16438/j.0513-4870.2021-0030
Year 2021 volume 56 Issue 9
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Article Info
doi: 10.16438/j.0513-4870.2021-0030
  • Receive Date:2021-01-06
  • Online Date:2025-12-18
  • Published:2021-09-12
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  • Received:2021-01-06
  • Revised:2021-03-22
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    State Key Laboratory of Bioactive Substance and Function of National Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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