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Application and prospect of alkyl polyglycosides absorption enhancers in drug delivery system
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Xian-fu LI, Zhi-wei ZHANG, Xiao-xuan HONG, Xiao-lu HAN, Meng LI, Zeng-ming WANG*, Ai-ping ZHENG*
Acta Pharmaceutica Sinica | 2021, 56(6) : 1591 - 1598
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Acta Pharmaceutica Sinica | 2021, 56(6): 1591-1598
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Application and prospect of alkyl polyglycosides absorption enhancers in drug delivery system
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Xian-fu LI, Zhi-wei ZHANG, Xiao-xuan HONG, Xiao-lu HAN, Meng LI, Zeng-ming WANG*, Ai-ping ZHENG*
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  • Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Academy of Military Sciences, Beijing 100850, China
Published: 2021-06-12 doi: 10.16438/j.0513-4870.2020-1882
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The efficient and safe delivery of drugs to the therapeutic site through the biofilm has traditionally been a difficult and hot topic in the field of drug delivery. In recent years, alkyl polyglycoside (APG) have become ideal penetration enhancers for drug delivery systems because of their high permeability, good safety and biodegradability, which has attracted wide attention of domestic and foreign researchers. In this paper, the physical and chemical properties, characteristics, action mechanism and application of APG in drug delivery system are reviewed, and its application prospect in drug delivery system is prospected.

alkyl polyglycoside  /  penetration enhancer  /  biofilm  /  safety  /  drug delivery system
Xian-fu LI, Zhi-wei ZHANG, Xiao-xuan HONG, Xiao-lu HAN, Meng LI, Zeng-ming WANG, Ai-ping ZHENG. Application and prospect of alkyl polyglycosides absorption enhancers in drug delivery system[J]. Acta Pharmaceutica Sinica, 2021 , 56 (6) : 1591 -1598 . DOI: 10.16438/j.0513-4870.2020-1882
Year 2021 volume 56 Issue 6
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Article Info
doi: 10.16438/j.0513-4870.2020-1882
  • Receive Date:2020-12-06
  • Online Date:2025-12-18
  • Published:2021-06-12
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  • Received:2020-12-06
  • Revised:2021-01-15
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    Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Academy of Military Sciences, Beijing 100850, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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