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Recent studies on the natural products with xanthine oxidase inhibitory effect
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Nan JIANG, Xiao-lin ZHANG, Jin-ying TIAN, Fei YE*
Acta Pharmaceutica Sinica | 2021, 56(5) : 1229 - 1237
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Acta Pharmaceutica Sinica | 2021, 56(5): 1229-1237
• Reviews •
Recent studies on the natural products with xanthine oxidase inhibitory effect
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Nan JIANG, Xiao-lin ZHANG, Jin-ying TIAN, Fei YE*
Affiliations
  • Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China
Published: 2021-05-12 doi: 10.16438/j.0513-4870.2020-1952
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Xanthine oxidase (XOD), catalyzing purine metabolism, is the key enzyme in uric acid (UA) biosynthesis, and becomes an important target for hyperuricemia treatment. The inhibition on XOD plays an important role in the treatment of hyperuricemia-related diseases, such as gout, as well as oxidative stress-induced tissue injury. Here, studies on the natural products with XOD inhibition are reviewed.

natural product  /  xanthine oxidase  /  uric acid  /  inhibition  /  hyperuricemia
Nan JIANG, Xiao-lin ZHANG, Jin-ying TIAN, Fei YE. Recent studies on the natural products with xanthine oxidase inhibitory effect[J]. Acta Pharmaceutica Sinica, 2021 , 56 (5) : 1229 -1237 . DOI: 10.16438/j.0513-4870.2020-1952
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Year 2021 volume 56 Issue 5
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Article Info
doi: 10.16438/j.0513-4870.2020-1952
  • Receive Date：2020-12-21
  • Online Date：2025-12-18
  • Published：2021-05-12
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  • Received：2020-12-21
  • Revised：2021-02-01
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    Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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