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Advances in structure and pharmacological function of temperature-sensitive TRPV2 channel
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Shu-wen XUE, Fan ZHANG*, Zheng-yu CAO*
Acta Pharmaceutica Sinica | 2021, 56(10) : 2720 - 2727
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Acta Pharmaceutica Sinica | 2021, 56(10): 2720-2727
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Advances in structure and pharmacological function of temperature-sensitive TRPV2 channel
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Shu-wen XUE, Fan ZHANG*, Zheng-yu CAO*
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  • College of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China
Published: 2021-10-12 doi: 10.16438/j.0513-4870.2021-0308
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Transient receptor potential vanilloid ion channel subtypes 2 (TRPV2) is a calcium permeable nonselective cation channel. TRPV2 is expressed in nerves, blood vessels, spleen, and other organs, and participates in the regulation of a variety of important physiological functions, such as nociception, neural development, and immune response. Here we reviewed the research progress on the structure, modulators, and physiological functions of TRPV2 channel to provide references for future research.

TRPV2  /  structure  /  modulator  /  physiological function
Shu-wen XUE, Fan ZHANG, Zheng-yu CAO. Advances in structure and pharmacological function of temperature-sensitive TRPV2 channel[J]. Acta Pharmaceutica Sinica, 2021 , 56 (10) : 2720 -2727 . DOI: 10.16438/j.0513-4870.2021-0308
Year 2021 volume 56 Issue 10
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Article Info
doi: 10.16438/j.0513-4870.2021-0308
  • Receive Date:2021-03-03
  • Online Date:2025-12-18
  • Published:2021-10-12
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  • Received:2021-03-03
  • Revised:2021-04-03
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    College of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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