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Analysis of the research status and intervention strategies for the treatment of hepatic encephalopathy based on gut microbiota regulation
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Jia-ting YIN, Yin PENG, Wen-hao XU, Meng-fei MAO, Jin-ao DUAN, Jian-ming GUO*
Acta Pharmaceutica Sinica | 2021, 56(4) : 895 - 905
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Acta Pharmaceutica Sinica | 2021, 56(4): 895-905
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Analysis of the research status and intervention strategies for the treatment of hepatic encephalopathy based on gut microbiota regulation
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Jia-ting YIN, Yin PENG, Wen-hao XU, Meng-fei MAO, Jin-ao DUAN, Jian-ming GUO*
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  • Jiangsu Key Laboratory of High Technology Research of TCM Formulae, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources, Nanjing University of Chinese Medicine, Nanjing 210023, China
Published: 2021-04-12 doi: 10.16438/j.0513-4870.2020-1222
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Hepatic encephalopathy is a common metabolic neuropsychiatric syndrome in the development of end-stage liver disease. Since the concept of intestinal-liver-brain axis was proposed, the relationship between the pathogenesis of hepatic encephalopathy and the gut microbiota has been a hot research topic. In recent years, studies have confirmed that gut microbiota is involved in and affects various pathological processes of hepatic encephalopathy. This article combines the latest research progress at home and abroad to elaborate on the research status of regulating gut microbiota and thus interfering with the pathological process of hepatic encephalopathy, hoping to provide new ideas and methods for the intervention of hepatic encephalopathy based on the regulation of gut microbiota.

gut microbiota  /  hepatic encephalopathy  /  therapy  /  pathogenesis  /  hyperammonemia
Jia-ting YIN, Yin PENG, Wen-hao XU, Meng-fei MAO, Jin-ao DUAN, Jian-ming GUO. Analysis of the research status and intervention strategies for the treatment of hepatic encephalopathy based on gut microbiota regulation[J]. Acta Pharmaceutica Sinica, 2021 , 56 (4) : 895 -905 . DOI: 10.16438/j.0513-4870.2020-1222
Year 2021 volume 56 Issue 4
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Article Info
doi: 10.16438/j.0513-4870.2020-1222
  • Receive Date:2020-07-22
  • Online Date:2025-12-18
  • Published:2021-04-12
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  • Received:2020-07-22
  • Revised:2020-08-10
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    Jiangsu Key Laboratory of High Technology Research of TCM Formulae, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources, Nanjing University of Chinese Medicine, Nanjing 210023, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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