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Research and application of nanometer black phosphorus in phototherapy and drug carrier
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Xin-meng LI, Jia-yue LI, Xin ZHANG, Sheng-ji TIAN, Shi-chao XIAO, Meng-yu YAO, Dan-qing LIU*, Ying GUO*
Acta Pharmaceutica Sinica | 2021, 56(1) : 178 - 189
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Acta Pharmaceutica Sinica | 2021, 56(1): 178-189
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Research and application of nanometer black phosphorus in phototherapy and drug carrier
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Xin-meng LI, Jia-yue LI, Xin ZHANG, Sheng-ji TIAN, Shi-chao XIAO, Meng-yu YAO, Dan-qing LIU*, Ying GUO*
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  • School of Chemistry and Environmental Engineering, Harbin University of Science and Technology, Harbin 150080, China
Published: 2021-01-12 doi: 10.16438/j.0513-4870.2020-1040
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The emerging nano-black phosphorus materials have created a new platform for biomedical research. Nano-black phosphorus has the following advantages: black phosphorus can produce singlet oxygen under near-infrared light irradiation, so it can be used as a photosensitizer for photodynamic therapy; black phosphorus has extensive light absorption in the long wavelength region, and this near-infrared photothermal property can be used in photothermal therapy. The high specific surface area and unique fold structure of the black phosphorus nanosheet make it have very high drug loading.This paper mainly reviews the applications of black phosphorus in biological imaging, photothermal therapy, photodynamic therapy, and as a drug carrier in recent years. Based on the photoelectric properties of black phosphorus nanomaterials combined with intelligent drug delivery platform, the synergistic effects of light/heat/chemistry, light/chemistry/gene, and light/chemistry/immunity can be produced, which has a broad application prospect.

black phosphorus  /  phototherapy  /  drug carrier  /  photodynamic  /  photothermal
Xin-meng LI, Jia-yue LI, Xin ZHANG, Sheng-ji TIAN, Shi-chao XIAO, Meng-yu YAO, Dan-qing LIU, Ying GUO. Research and application of nanometer black phosphorus in phototherapy and drug carrier[J]. Acta Pharmaceutica Sinica, 2021 , 56 (1) : 178 -189 . DOI: 10.16438/j.0513-4870.2020-1040
Year 2021 volume 56 Issue 1
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doi: 10.16438/j.0513-4870.2020-1040
  • Receive Date:2020-06-23
  • Online Date:2025-12-18
  • Published:2021-01-12
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  • Received:2020-06-23
  • Revised:2020-08-01
Affiliations
    School of Chemistry and Environmental Engineering, Harbin University of Science and Technology, Harbin 150080, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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