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A new xanthone from the Polygala tenuifolia Willd. of northern Shaanxi
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Yun-peng JIA1, Lu LIU1, Xiao-jun YANG1, *, Chao WANG1, Huo-bing REN2
Acta Pharmaceutica Sinica | 2024, 59(3) : 667 - 672
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Acta Pharmaceutica Sinica | 2024, 59(3): 667-672
• Original Articles •
A new xanthone from the Polygala tenuifolia Willd. of northern Shaanxi
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Yun-peng JIA1, Lu LIU1, Xiao-jun YANG1, *, Chao WANG1, Huo-bing REN2
Affiliations
  • 1. College of Chemistry and Chemical Engineering, Yan'an University, Yan′an 716000, China
  • 2. Shaanxi Yuankang Traditional Chinese Medicine Industry Development Co., Ltd., Suide 718000, China
Published: 2024-03-12 doi: 10.16438/j.0513-4870.2023-0919
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Ten compounds were isolated and purified from ethanol extracts of dried roots bark of Polygala tenuifolia Willd. by various chromatography techniques such as silica gel and Sephadex LH-20. Their structures were identified by analysis of physicochemical properties and spectral data, and determined as β-sitosterol (1), tenuifolin (2), 6-methoxy coumarin (3), 7-phenyl-1-hydroxy-2, 3, 6-trimethoxyxanthone (4), 1, 8-dihydroxy-3, 4, 7-trimethoxyanthone (5), mangiferin (6), quercetin-3-O-β-D-glucoside (7), rutin (8), syringaldehyde (9), salicylicacid (10). Among them, compounds 3, 4 and 5 were isolated from the genus of Ploygala for the first time and compound 4 was a new xanthone. The acetylcholinesterase inhibitory activities of compounds 3, 4 and 5 were evaluated by Ellman colorimetric method, compounds 3 and 5 exhibited moderate inhibitory activity, compound 4 exhibited weak inhibitory activity.

Polygala tenuifolia Willd.  /  chemical composition  /  xanthone  /  acetylcholinesterase inhibitory activity
Yun-peng JIA, Lu LIU, Xiao-jun YANG, Chao WANG, Huo-bing REN. A new xanthone from the Polygala tenuifolia Willd. of northern Shaanxi[J]. Acta Pharmaceutica Sinica, 2024 , 59 (3) : 667 -672 . DOI: 10.16438/j.0513-4870.2023-0919
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Year 2024 volume 59 Issue 3
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Article Info
doi: 10.16438/j.0513-4870.2023-0919
  • Receive Date：2023-07-27
  • Online Date：2025-11-28
  • Published：2024-03-12
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  • Received：2023-07-27
  • Revised：2023-09-19
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    1. College of Chemistry and Chemical Engineering, Yan'an University, Yan′an 716000, China
    2. Shaanxi Yuankang Traditional Chinese Medicine Industry Development Co., Ltd., Suide 718000, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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