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The underlying logic, innovative thinking and research paradigm of antiviral medicinal chemistry
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Shuo WANG1, Bao-hu LI1, 2, Shu-jing XU1, Yang ZHOU1, Jin-fei YANG2, Xin-yong LIU1, Peng ZHAN1, *
Acta Pharmaceutica Sinica | 2024, 59(7) : 1916 - 1931
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Acta Pharmaceutica Sinica | 2024, 59(7): 1916-1931
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The underlying logic, innovative thinking and research paradigm of antiviral medicinal chemistry
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Shuo WANG1, Bao-hu LI1, 2, Shu-jing XU1, Yang ZHOU1, Jin-fei YANG2, Xin-yong LIU1, Peng ZHAN1, *
Affiliations
  • 1. Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
  • 2. School of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao 266001, China
Published: 2024-07-12 doi: 10.16438/j.0513-4870.2024-0131
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Antiviral drug research and development is an important research direction in the current and future biomedical field. The research and development of antiviral drugs not only requires the application of new strategies and new technologies, but also requires the complementary advantages and close cooperation of project teams. Based on the latest progress in this field and the author's drug research practice, this paper summarizes the underlying logic, innovative thinking and research paradigm of antiviral medicinal chemistry.

medicinal chemistry  /  viral infection  /  drug design  /  research paradigm  /  small molecule drug
Shuo WANG, Bao-hu LI, Shu-jing XU, Yang ZHOU, Jin-fei YANG, Xin-yong LIU, Peng ZHAN. The underlying logic, innovative thinking and research paradigm of antiviral medicinal chemistry[J]. Acta Pharmaceutica Sinica, 2024 , 59 (7) : 1916 -1931 . DOI: 10.16438/j.0513-4870.2024-0131
Year 2024 volume 59 Issue 7
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doi: 10.16438/j.0513-4870.2024-0131
  • Receive Date:2024-02-16
  • Online Date:2025-11-26
  • Published:2024-07-12
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  • Received:2024-02-16
  • Revised:2024-05-05
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    1. Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
    2. School of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao 266001, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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