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Research progress on cardiovascular toxicity associated with anti-tumor drugs and its prevention and treatment
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Ya-lin YANG1, Yang HU2, Jian-dong JIANG1, Yu-hong WANG1, *, Zhen-yu LIU3, *
Acta Pharmaceutica Sinica | 2023, 58(12) : 3539 - 3548
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Acta Pharmaceutica Sinica | 2023, 58(12): 3539-3548
Research progress on cardiovascular toxicity associated with anti-tumor drugs and its prevention and treatment
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Ya-lin YANG1, Yang HU2, Jian-dong JIANG1, Yu-hong WANG1, *, Zhen-yu LIU3, *
Affiliations
  • 1. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
  • 2. Department of Pharmacy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
  • 3. Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Published: 2023-12-12 doi: 10.16438/j.0513-4870.2023-0324
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Cancer and cardiovascular diseases are the two major causes of death worldwide. The application of anti-tumor drugs has significantly improved the prognosis of patients, the cardiovascular toxicity caused by the application of them has become an important factor affecting the survival and prognosis of cancer patients. Therefore, the prevention and treatment of cardiovascular toxicity related to cancer treatment is increasingly important. The cardiovascular toxicity associated with anti-tumor drugs exhibits different clinical manifestations and involves multiple pathological mechanisms. This article reviews the current research progress from the perspective of the characteristics, molecular mechanisms and prevention and treatment strategies of cardiovascular toxicity caused by cancer drugs.

anti-tumor drug  /  cardiac toxicity  /  vascular toxicity  /  pathological mechanism  /  prevention and treatment
Ya-lin YANG, Yang HU, Jian-dong JIANG, Yu-hong WANG, Zhen-yu LIU. Research progress on cardiovascular toxicity associated with anti-tumor drugs and its prevention and treatment[J]. Acta Pharmaceutica Sinica, 2023 , 58 (12) : 3539 -3548 . DOI: 10.16438/j.0513-4870.2023-0324
Year 2023 volume 58 Issue 12
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Article Info
doi: 10.16438/j.0513-4870.2023-0324
  • Receive Date:2023-03-16
  • Online Date:2025-11-21
  • Published:2023-12-12
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History
  • Received:2023-03-16
  • Revised:2023-06-06
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Affiliations
    1. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    2. Department of Pharmacy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
    3. Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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