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Rapid identification of the chemical compounds in the leaves of Solanum nigrum L. based on UHPLC-Q Exactive MS and molecular network technology
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Xian-long DONG, Lin-jiao YANG, Xue-mei QIN, Zhen-yu LI*
Acta Pharmaceutica Sinica | 2023, 58(4) : 1003 - 1013
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Acta Pharmaceutica Sinica | 2023, 58(4): 1003-1013
Rapid identification of the chemical compounds in the leaves of Solanum nigrum L. based on UHPLC-Q Exactive MS and molecular network technology
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Xian-long DONG, Lin-jiao YANG, Xue-mei QIN, Zhen-yu LI*
Affiliations
  • Modern Research Center for Traditional Chinese Medicine, the Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030006, China
Published: 2023-04-12 doi: 10.16438/j.0513-4870.2022-1162
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The whole herb of Solanum nigrum L. can be used as the herbal drug. In this study, UHPLC-Q Exactive high resolution mass combined with GNPS molecular network was used for the rapid characterization of the components in the leaves of S. nigrum L. A total of 157 compounds were identified, including 30 steroid alkaloids, 61 steroid saponins, 35 flavonoids, and 31 other compounds (amino acids and organic acids), by comparison with the data reported in the literature, and mass fragmentation characteristics analysis, as well as the correlation of known and unknown nodes in the GNPS molecular network. Compared with the fruits and stems, the leaves of S. nigrum L was rich in a variety of steroidal saponins, steroidal alkaloids, and flavonoids, and the results lay the foundation for the precise resources utilization of S. nigrum L.

UHPLC-Q Exactive MS  /  Solanum nigrum L.  /  GNPS molecular network  /  steroid alkaloids  /  steroid saponins  /  flavonoids
Xian-long DONG, Lin-jiao YANG, Xue-mei QIN, Zhen-yu LI. Rapid identification of the chemical compounds in the leaves of Solanum nigrum L. based on UHPLC-Q Exactive MS and molecular network technology[J]. Acta Pharmaceutica Sinica, 2023 , 58 (4) : 1003 -1013 . DOI: 10.16438/j.0513-4870.2022-1162
Year 2023 volume 58 Issue 4
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Article Info
doi: 10.16438/j.0513-4870.2022-1162
  • Receive Date:2022-11-01
  • Online Date:2025-11-21
  • Published:2023-04-12
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  • Received:2022-11-01
  • Revised:2023-03-14
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    Modern Research Center for Traditional Chinese Medicine, the Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030006, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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