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Clinical application and pharmacokinetic study of nanocarriers in drug delivery system
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Xiao XIAO, Jun-yu CHEN, Cai-xia LI, Man WU, Jian-dang LI, Chang-kuo SHI, Shu-qing WU, Wen-liang LI*
Acta Pharmaceutica Sinica | 2023, 58(4) : 856 - 866
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Acta Pharmaceutica Sinica | 2023, 58(4): 856-866
Clinical application and pharmacokinetic study of nanocarriers in drug delivery system
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Xiao XIAO, Jun-yu CHEN, Cai-xia LI, Man WU, Jian-dang LI, Chang-kuo SHI, Shu-qing WU, Wen-liang LI*
Affiliations
  • School of Pharmacy, Antibody Center, Jilin Medical University, Jilin 132013, China
Published: 2023-04-12 doi: 10.16438/j.0513-4870.2022-1090
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Nanotechnology has shown obvious advantages in the field of medical treatment and diagnosis. Through the encapsulation of nano carriers, drugs not only enhance the therapeutic effect and reduce toxic and side effects, but also become intelligent responsive targeted drug systems through the modification on the surface of nano carriers. However, due to the obstacles in relevant basic research, production conditions, cost, clinical trials, and the lack of pharmacokinetic research on various drug loading systems, few nano systems have been used in therapy. In order to solve the above problems, this paper reviewed and analyzed the research progress of nano carriers in drug delivery, including their auxiliary role and characteristics, types and functions, pharmacokinetics, application prospects and challenges.

nanocarrier  /  drug delivery  /  pharmacokinetics  /  nanomedicine  /  targeted delivery
Xiao XIAO, Jun-yu CHEN, Cai-xia LI, Man WU, Jian-dang LI, Chang-kuo SHI, Shu-qing WU, Wen-liang LI. Clinical application and pharmacokinetic study of nanocarriers in drug delivery system[J]. Acta Pharmaceutica Sinica, 2023 , 58 (4) : 856 -866 . DOI: 10.16438/j.0513-4870.2022-1090
Year 2023 volume 58 Issue 4
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Article Info
doi: 10.16438/j.0513-4870.2022-1090
  • Receive Date:2022-10-04
  • Online Date:2025-11-21
  • Published:2023-04-12
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  • Received:2022-10-04
  • Revised:2023-02-02
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    School of Pharmacy, Antibody Center, Jilin Medical University, Jilin 132013, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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