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From Golgiphagy to Golgimedicine — a new strategy for disease prevention and treatment targeting the Golgi apparatus
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Cheng-xiao FU1, 2, Lin-xi CHEN1, *
Acta Pharmaceutica Sinica | 2025, 60(2) : 280 - 287
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Acta Pharmaceutica Sinica | 2025, 60(2): 280-287
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From Golgiphagy to Golgimedicine — a new strategy for disease prevention and treatment targeting the Golgi apparatus
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Cheng-xiao FU1, 2, Lin-xi CHEN1, *
Affiliations
  • 1. Institute of Pharmacy and Pharmacology, School of Pharmaceutical Science, University of South China, Hengyang 421001, China
  • 2. Department of Pharmacy, the First Affiliated Hospital, University of South China, Hengyang 421001, China
Published: 2025-02-12 doi: 10.16438/j.0513-4870.2024-0994
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Functional disorders of the Golgi apparatus are harmful to the health of organisms, leading to various diseases. Removing damaged Golgi apparatus is crucial for maintaining cellular homeostasis, therefore, autophagy of Golgi apparatus has gradually attracted attention. This article summarizes Golgi autophagy, briefly describes its structure and functions, Golgi autophagy receptors, and the role of Golgi autophagy in disease treatment. It also proposes the new concept of Golgimedicine, which looks forward to the role of Golgi in disease diagnosis, treatment, prognosis, genetic diseases, and rare diseases. This article aims to explore the scientific connotations of Golgi autophagy, Golgi structure and function from the perspective of Golgimedicine, providing theoretical references for drug target research, new drug development, and the healthy development of humanity.

Golgi apparatus  /  Golgiphagy  /  Golgimedicine  /  organelle  /  disease prevention and treatment
Cheng-xiao FU, Lin-xi CHEN. From Golgiphagy to Golgimedicine — a new strategy for disease prevention and treatment targeting the Golgi apparatus[J]. Acta Pharmaceutica Sinica, 2025 , 60 (2) : 280 -287 . DOI: 10.16438/j.0513-4870.2024-0994
Year 2025 volume 60 Issue 2
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Article Info
doi: 10.16438/j.0513-4870.2024-0994
  • Receive Date:2024-10-15
  • Online Date:2025-11-07
  • Published:2025-02-12
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  • Received:2024-10-15
  • Revised:2024-11-22
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    1. Institute of Pharmacy and Pharmacology, School of Pharmaceutical Science, University of South China, Hengyang 421001, China
    2. Department of Pharmacy, the First Affiliated Hospital, University of South China, Hengyang 421001, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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