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Research progress of natural bioactive products in resisting loss of skin collagen
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Chu-juan HU, Lu-lu WANG, Jian-dong JIANG, Rui LI*
Acta Pharmaceutica Sinica | 2025, 60(2) : 269 - 279
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Acta Pharmaceutica Sinica | 2025, 60(2): 269-279
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Research progress of natural bioactive products in resisting loss of skin collagen
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Chu-juan HU, Lu-lu WANG, Jian-dong JIANG, Rui LI*
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  • Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2025-02-12 doi: 10.16438/j.0513-4870.2024-0871
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As the biggest tissue of human body, skin is the first barrier of resisting external aggression. Collagen is one of important parts of the skin, which could not only affect the aesthetics of skin, but also influence the health and normal function of skin. It is the great significance to find ways that could inhibit the loss of collagen. The mechanisms of the collagen degradation in skin are complex and multifaceted. Natural bioactive products have unique advantages in treating the loss of collagen, which have multi-targets and mechanisms. In this review, the mechanisms of skin collagen degradation are discussed, and the research progress of natural bioactive products in resisting skin aging through promoting collagen synthesis are reviewed, in order to provide references for futural research.

collagen  /  natural bioactive product  /  skin aging  /  mitochondria
Chu-juan HU, Lu-lu WANG, Jian-dong JIANG, Rui LI. Research progress of natural bioactive products in resisting loss of skin collagen[J]. Acta Pharmaceutica Sinica, 2025 , 60 (2) : 269 -279 . DOI: 10.16438/j.0513-4870.2024-0871
Year 2025 volume 60 Issue 2
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doi: 10.16438/j.0513-4870.2024-0871
  • Receive Date:2024-09-06
  • Online Date:2025-11-07
  • Published:2025-02-12
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  • Received:2024-09-06
  • Revised:2024-10-30
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    Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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