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A new seco-amorphane-type sesquiterpenoid from Artemisia annua L.
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Dao-zeng ZOU, Fu-jie XU, Ji-qiao YUAN, Man-yuan WANG*
Acta Pharmaceutica Sinica | 2025, 60(5) : 1490 - 1493
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Acta Pharmaceutica Sinica | 2025, 60(5): 1490-1493
Original Articles
A new seco-amorphane-type sesquiterpenoid from Artemisia annua L.
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Dao-zeng ZOU, Fu-jie XU, Ji-qiao YUAN, Man-yuan WANG*
Affiliations
  • School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China
Published: 2025-05-12 doi: 10.16438/j.0513-4870.2024-1247
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Four terpenoids were isolated from the neutral portion of petroleum ether extract of Artemisia annua by several chromatographic methods, such as silica gel, MCI Gel CHP-20, ODS, Sephadex LH-20 and semi-preparative HPLC. Their structures were identified by HR-MS and nuclear magnetic resonance spectroscopy. These compounds were defined as (1S,4S,5R,6S,9R,10R)-4-ethoxy-9,10-dimethyloctahydrofuro-(3,2-i)-isochromen-11(4H)-one (1), 3a,4,5,6,6a,7-hexahydro-3,6-dimethyl-9-methyl-2H-naphtho[8a,1-b]furan-2,8(3H)-dione (2), kobusone (3) and 1,2-campholide (4). Compound 1 is a new compound, of which the absolute configuration was established by single crystal X-ray crystallographic analysis. Compound 2 is a new natural product. Compounds 3 and 4 are first isolated from the Artemisia genus.

Artemisia annua L.  /  chemical constituent  /  seco-amorphane-type sesquiterpenoid  /  new natural product
Dao-zeng ZOU, Fu-jie XU, Ji-qiao YUAN, Man-yuan WANG. A new seco-amorphane-type sesquiterpenoid from Artemisia annua L.[J]. Acta Pharmaceutica Sinica, 2025 , 60 (5) : 1490 -1493 . DOI: 10.16438/j.0513-4870.2024-1247
Year 2025 volume 60 Issue 5
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Article Info
doi: 10.16438/j.0513-4870.2024-1247
  • Receive Date:2024-12-15
  • Online Date:2025-10-29
  • Published:2025-05-12
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  • Received:2024-12-15
  • Revised:2025-01-17
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    School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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