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The chemical constituents of petroleum ether extracts from the whole plant of Ferula bungeana were isolated using chromatographic techniques such as SiO2, Sephadex LH-20, and thin-layer chromatography. Their structures were determined through the analysis of their spectral data. Five sesquiterpenoids were identified from the petroleum ether extracts of Ferula bungeana whole plant, namely buntone A (1), caryophyllene oxide (2), eudesol (3), mesoferulone (4), and jaeschkeanadiol (5). Among them, compound 1 was a new sesquiterpene lactone, while compounds 2 and 3 were isolated for the first time from the genus Ferula. Compounds 1-3 were screened for in vitro anti-inflammatory activity, and the results showed that compounds 1-3 exhibited varying degrees of NO inhibitory activity at a concentration of 10 μmol·L-1, with inhibition rates of 89.8% ± 1.2%, 76.4% ± 0.8% and 80.4% ± 0.9%, respectively.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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