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Two new cyclic dipeptides with hydroxyisobutyl side chains from Angelica dahurica
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Chun-xia XIAO1, Fan-lin TANG1, Jin-ke LI1, Xiao-xue SUN1, Feng ZHANG1, 2, *, Bao-shun ZHANG1, *
Acta Pharmaceutica Sinica | 2026, 61(6) : 2241 - 2244
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Acta Pharmaceutica Sinica | 2026, 61(6): 2241-2244
• Original Articles •
Two new cyclic dipeptides with hydroxyisobutyl side chains from Angelica dahurica
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Chun-xia XIAO1, Fan-lin TANG1, Jin-ke LI1, Xiao-xue SUN1, Feng ZHANG1, 2, *, Bao-shun ZHANG1, *
Affiliations
  • 1College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China
  • 2Jiangsu Province Hospital of Chinese Medicine Chongqing Hospital, Chongqing 402105, China
Published: 2026-06-12 doi: 10.16438/j.0513-4870.2026-0142
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Using various separation and purification techniques including silica gel and recrystallization, two new cyclic dipeptides involving non-proteinogenic amino acids were first isolated and purified from the ethyl acetate fraction of the ethanol (95%) extract of Angelica dahurica. Through the modern spectroscopic methods such as NMR, HR-ESI-MS, IR, OR, UV, and CD, their structures were identified as angelidaphine A (1) and angelidaphine B (2).

Angelica dahurica  /  chemical composition  /  cyclic dipeptide
肖春霞, 唐凡淋, 李金科, 孙孝雪, 张锋, 张保顺. 白芷中两个具有羟基异丁基侧链的新环二肽类化合物. 药学学报, 2026 , 61 (6) : 2241 -2244 . DOI: 10.16438/j.0513-4870.2026-0142
Chun-xia XIAO, Fan-lin TANG, Jin-ke LI, Xiao-xue SUN, Feng ZHANG, Bao-shun ZHANG. Two new cyclic dipeptides with hydroxyisobutyl side chains from Angelica dahurica[J]. Acta Pharmaceutica Sinica, 2026 , 61 (6) : 2241 -2244 . DOI: 10.16438/j.0513-4870.2026-0142
Year 2026 volume 61 Issue 6
195
88
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Article Info
doi: 10.16438/j.0513-4870.2026-0142
  • Receive Date:2026-02-02
  • Online Date:2026-09-21
  • Published:2026-06-12
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  • Received:2026-02-02
  • Revised:2026-04-03
Affiliations
    1College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China
    2Jiangsu Province Hospital of Chinese Medicine Chongqing Hospital, Chongqing 402105, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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