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Chemical constituents from Meiogyne hainanensis
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Ting-liang LIU1, 2, Tian-tian WANG3, Wen-lin ZHENG1, 2, Jia-zheng WU1, 2, Shi-yun DU2, Zhen-dan HE2, Yan WU2, 4, *
Acta Pharmaceutica Sinica | 2026, 61(5) : 1769 - 1776
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Acta Pharmaceutica Sinica | 2026, 61(5): 1769-1776
• Original Articles •
Chemical constituents from Meiogyne hainanensis
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Ting-liang LIU1, 2, Tian-tian WANG3, Wen-lin ZHENG1, 2, Jia-zheng WU1, 2, Shi-yun DU2, Zhen-dan HE2, Yan WU2, 4, *
Affiliations
  • 1School of Pharmacy, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China
  • 2College of Pharmacy, Shenzhen Technology University, Shenzhen 518118, China
  • 3School of Pharmacy, Henan University, Kaifeng 475004, China
  • 4International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China, Jinan University, Guangzhou 510632, China
Published: 2026-05-12 doi: 10.16438/j.0513-4870.2025-1429
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Thirteen compounds were isolated from the twigs and leaves of Meiogyne hainanensis (Merr.) N. T. Ban by silica gel column chromatography, sephadex LH-20, and preparative HPLC. Their structures were respectively determined as chienhainanin N (1), (S)-15, 16-didehydrocoriolic acid methyl ester (2), 13-hydroxy-9Z, 11E, 15E-octadecatrienoic acid (3), (S)-coriolic acid (4), 13-oxo-(9Z, 11E)-octadecadienic acid (5), 13-oxo-(9E, 11E)-octadecadienic acid (6), 9-oxo-(10E, 12Z)-octadecadienic acid (7), 9-oxo-(10E, 12E)-octadecadienic acid (8), α-tocopherol (9), vitamin E quinone (10), α-tocospiro A (11), 17c-ethoxypheaophorbide A (12), mustakone (13) by spectral data analysis. Among them, compound 1 is a new compound, compounds 2, 3, 5-8, 10-12 are isolated from Annonaceae plants for the first time, and compounds 4, 9 and 13 are isolated from the genus Meiogyne for the first time. Their antimicrobial activities were evaluated by the broth microdilution method. Compounds 2, 3, 5-7 showed weak antimicrobial effect against MRSA with MIC values from 64 to128 μg·mL-1, respectively. Compound 13 showed weak antimicrobial effects against Cryptococcus neoformans with the MIC value of 128 μg·mL-1.

Meiogyne hainanensis  /  Annonaceae  /  Meiogyne  /  chemical constituent  /  antimicrobial activity
刘庭亮, 王甜甜, 郑文琳, 吴嘉正, 杜世云, 贺震旦, 吴炎. 蕉木的化学成分研究. 药学学报, 2026 , 61 (5) : 1769 -1776 . DOI: 10.16438/j.0513-4870.2025-1429
Ting-liang LIU, Tian-tian WANG, Wen-lin ZHENG, Jia-zheng WU, Shi-yun DU, Zhen-dan HE, Yan WU. Chemical constituents from Meiogyne hainanensis[J]. Acta Pharmaceutica Sinica, 2026 , 61 (5) : 1769 -1776 . DOI: 10.16438/j.0513-4870.2025-1429
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Year 2026 volume 61 Issue 5
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Article Info
doi: 10.16438/j.0513-4870.2025-1429
  • Receive Date：2025-12-01
  • Online Date：2026-09-21
  • Published：2026-05-12
Article Data
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History
  • Received：2025-12-01
  • Revised：2026-01-05
Affiliations
    1School of Pharmacy, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China
    2College of Pharmacy, Shenzhen Technology University, Shenzhen 518118, China
    3School of Pharmacy, Henan University, Kaifeng 475004, China
    4International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China, Jinan University, Guangzhou 510632, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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