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Outline
As indispensable medications in the medical field, antibiotics face severe challenges such as high pollution and high energy consumption in their traditional chemical synthesis processes. The novel enzymatic catalytic process, leveraging the catalytic properties of enzymes and the advantages of environmental friendliness, has emerged as a new direction for the green development of the antibiotic industry. This paper focuses on the application progress of the novel enzymatic catalytic process in the green synthesis of antibiotics, systematically elaborates on its catalytic mechanism, and analyzes the specific applications and advantages of this process in the production of antibiotics such as β-lactams, aminoglycosides, and macrolides. Meanwhile, it points out the issue that catalyst residues during the production process affect the quality and safety of pharmaceutical products, and discusses the current challenges confronted by the novel enzymatic catalytic process for antibiotics. Finally, by applying cutting-edge technologies including synthetic biology and artificial intelligence, this paper provides a theoretical basis and solutions for breaking through existing technical limitations and promoting the green upgrading of the antibiotic industry.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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