Full
Outline
Breast cancer is one of the prevalent malignant tumors among women worldwide. Conventional treatment strategies often suffer from systemic toxicity, strong drug resistance, and limited targeting capability. In recent years, with advances in biomaterials and drug delivery technologies, microneedles have emerged as a novel transdermal delivery platform offering advantages such as minimal invasiveness, precise targeting, and efficient delivery. These features render microneedles particularly promising for breast cancer therapy. This review summarizes recent progress in the application of microneedle drug delivery systems in breast cancer, including their use in delivering antitumor agents, immunotherapy, photothermal/photodynamic therapy, among others. The mechanisms of action and therapeutic advantages are discussed, along with current challenges and future prospects, aiming to provide a theoretical basis for the translational application of microneedles in breast cancer treatment.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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