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Acne treatment based on drug delivery technology
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Bing AI1, 2, Hui-ling LIAO3, Jia-li LIAO1, 2, Ya-ping LIU3, Zhen-feng WU1, 2, *, Wei HE1, 2, *
Acta Pharmaceutica Sinica | 2025, 60(10) : 3019 - 3035
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Acta Pharmaceutica Sinica | 2025, 60(10): 3019-3035
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Acne treatment based on drug delivery technology
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Bing AI1, 2, Hui-ling LIAO3, Jia-li LIAO1, 2, Ya-ping LIU3, Zhen-feng WU1, 2, *, Wei HE1, 2, *
Affiliations
  • 1Key Lab of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Chinese Medicine, Nanchang 330004, China
  • 2Jiangxi Green Manufacturing Technology Innovation Center for Traditional Chinese Medicine, Nanchang 330115, China
  • 3School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
Published: 2025-10-12 doi: 10.16438/j.0513-4870.2025-0344
Outline
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Acne vulgaris is a chronic inflammatory skin disease, mainly caused by clogged and inflamed hair follicles, and is the eighth most common disease worldwide, severely affecting people's quality of life. Although several treatment options are available, such as pharmacotherapy and physiotherapy, most medications suffer from significant side effects, poor chemical stability, and low targeting efficacy. Drug delivery systems (DDS) have potential applications in acne treatment, particularly in enhancing drug efficacy and minimizing side effects. Therefore, the development of novel DDS has become the focus of current research. This review firstly analyzes the pathological mechanisms of acne vulgaris and its therapeutic targets, secondly systematically outlines the existing therapeutic approaches, and finally focuses on the potential applications of DDS in acne treatment, aiming to provide new perspectives and options for future acne treatment.

acne vulgaris  /  drug delivery system  /  pathomechanism  /  therapeutic approach  /  nanocarrier  /  targeted delivery  /  deep eutectic solvent  /  transdermal drug delivery
艾兵, 廖慧玲, 廖佳丽, 刘亚萍, 伍振峰, 何伟. 基于药物递送技术的痤疮治疗. 药学学报, 2025 , 60 (10) : 3019 -3035 . DOI: 10.16438/j.0513-4870.2025-0344
Bing AI, Hui-ling LIAO, Jia-li LIAO, Ya-ping LIU, Zhen-feng WU, Wei HE. Acne treatment based on drug delivery technology[J]. Acta Pharmaceutica Sinica, 2025 , 60 (10) : 3019 -3035 . DOI: 10.16438/j.0513-4870.2025-0344
Year 2025 volume 60 Issue 10
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Article Info
doi: 10.16438/j.0513-4870.2025-0344
  • Receive Date:2025-03-29
  • Online Date:2026-09-20
  • Published:2025-10-12
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History
  • Received:2025-03-29
  • Revised:2025-07-08
Affiliations
    1Key Lab of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Chinese Medicine, Nanchang 330004, China
    2Jiangxi Green Manufacturing Technology Innovation Center for Traditional Chinese Medicine, Nanchang 330115, China
    3School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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