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Research progress of nuclear bodies in tumor
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Qing-yuan LIU, Yun-yao LIU*, Yi-ting XU, Yu-jiao XU, Lei QIANG*
Acta Pharmaceutica Sinica | 2024, 59(12) : 3179 - 3188
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Acta Pharmaceutica Sinica | 2024, 59(12): 3179-3188
Research progress of nuclear bodies in tumor
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Qing-yuan LIU, Yun-yao LIU*, Yi-ting XU, Yu-jiao XU, Lei QIANG*
Affiliations
  • School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210000, China
Published: 2024-12-12 doi: 10.16438/j.0513-4870.2024-0597
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The mammalian cell nucleus is highly structured and organized into various membrane-less nuclear compartments called nuclear bodies. Nuclear bodies are highly dynamic structures, with a variety of substances gathered inside to promote the more efficient conduct of certain biological reactions. It dynamically produces responses under different biological processes and stress conditions such as tumorigenesis, apoptosis, antiviral defense, and plays an important role in regulating cell homeostasis. Tumor is a major public health problem, and finding new targets is the key to tumor therapy. How the nuclear bodies are involved in the development of tumor has not been reported. This review aims to provide a new understanding of how the nuclear bodies regulates tumor progression and provide a new effective strategy for tumor prevention and treatment.

nuclear body  /  nucleolus  /  promyelocytic leukemia nuclear body  /  nuclear speckle  /  paraspeckle  /  tumor
Qing-yuan LIU, Yun-yao LIU, Yi-ting XU, Yu-jiao XU, Lei QIANG. Research progress of nuclear bodies in tumor[J]. Acta Pharmaceutica Sinica, 2024 , 59 (12) : 3179 -3188 . DOI: 10.16438/j.0513-4870.2024-0597
Year 2024 volume 59 Issue 12
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doi: 10.16438/j.0513-4870.2024-0597
  • Receive Date:2024-06-25
  • Online Date:2025-11-24
  • Published:2024-12-12
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  • Received:2024-06-25
  • Revised:2024-09-23
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    School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210000, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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