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Biological principles of "food and medicine homologous"
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Jin-wen DING1, Xiang-yin CHI1, Yu ZHANG1, Lu-lu WANG2, Jian-dong JIANG1, 2, *, Yuan LIN1, *
Acta Pharmaceutica Sinica | 2024, 59(6) : 1509 - 1518
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Acta Pharmaceutica Sinica | 2024, 59(6): 1509-1518
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Biological principles of "food and medicine homologous"
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Jin-wen DING1, Xiang-yin CHI1, Yu ZHANG1, Lu-lu WANG2, Jian-dong JIANG1, 2, *, Yuan LIN1, *
Affiliations
  • 1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
  • 2. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2024-06-12 doi: 10.16438/j.0513-4870.2024-0284
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With the rapid society development and broad recognition of "Healthy China", the demands for good life and health are increasing. Accordingly, the concept of "food and medicine homologous" have been attractive. The concept of "food and medicine homologous" has a long history in China, and is an essence of various ideas in traditional Chinese medicine, such as diet therapy, medicated diet, regimen and preventive treatment of disease, representing an important field in health science. Many studies have found that the active ingredients of "food and medicine homologous" substances are multiple types, multiple mechanisms and multiple targets, exerting their biological effects after oral administration and chemical or metabolic transformation. In this review, the chemical basis and biological principles of various "food and medicine homologous" substances were summarized as compounds, biological macromolecules and intestinal flora. By focusing on the intestinal flora, we discussed the detailed biological principles of several classic "food and medicine homologous" substances. The scientific significance of "food and medicine homologous" concept were also discussed. This review explores the concept of "food and medicine homologous" from the perspective of modern medicine, in order to provide insights for future drug development and human health.

food and medicine homologous  /  preventive treatment of disease  /  intestinal flora  /  chemical basis  /  pharmacological activity  /  Biao Ben Jian Zhi
Jin-wen DING, Xiang-yin CHI, Yu ZHANG, Lu-lu WANG, Jian-dong JIANG, Yuan LIN. Biological principles of "food and medicine homologous"[J]. Acta Pharmaceutica Sinica, 2024 , 59 (6) : 1509 -1518 . DOI: 10.16438/j.0513-4870.2024-0284
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Article Info
doi: 10.16438/j.0513-4870.2024-0284
  • Receive Date：2024-03-28
  • Online Date：2025-11-26
  • Published：2024-06-12
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History
  • Received：2024-03-28
  • Revised：2024-04-22
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Affiliations
    1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    2. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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