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Chemical constituents of dichloromethane extract from the stems of Ephedra intermedia
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Xi-ling FAN1, 2, Yan-gang CAO1, 2, Xiao-ke ZHENG1, 2, 3, Zhen-zhong WANG4, Wei XIAO4, Wei-sheng FENG1, 2, 3, *
Acta Pharmaceutica Sinica | 2024, 59(9) : 2574 - 2580
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Acta Pharmaceutica Sinica | 2024, 59(9): 2574-2580
Chemical constituents of dichloromethane extract from the stems of Ephedra intermedia
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Xi-ling FAN1, 2, Yan-gang CAO1, 2, Xiao-ke ZHENG1, 2, 3, Zhen-zhong WANG4, Wei XIAO4, Wei-sheng FENG1, 2, 3, *
Affiliations
  • 1. Henan University of Chinese Medicine, Zhengzhou 450046, China
  • 2. Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou 450046, China
  • 3. Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan Province and Ministry of Education of China, Zhengzhou 450046, China
  • 4. State Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Lianyungang 222001, China
Published: 2024-09-12 doi: 10.16438/j.0513-4870.2024-0168
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Ten compounds were isolated and purified from the dichloromethane extract of stems of Ephedra intermedia by various chromatographic methods. Based on the analysis of physicochemical properties and spectral data, the structures of the ten compounds were identified as 1-allyl-3, 4-dimethoxy-benzene-5-O-β-D-glucopyranoside (1), lyoniresinol (2), secoisolariciresinol (3), 4, 3′, 4′-trihydroxy-3-methoxylignan-9, 9′-diyldiacetate (4), dehydroconiferyl alcohol (5), isocubebin (6), balanophonin B (7), sesquipinsapol B (8), crataegifin A (9), 1-(2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2, 3-dihydrobenzofuran-5-yl)ethan-1-one (10). Compound 1 is a new compound, named as 1-allyl-3, 4-dimethhoxy-benzene-5-O-β-D-glucopyranosyl, compounds 2-10 are lignans and isolated from this plant for the first time. Compound 3, 4, 8 possess potentially anti-asthmatic activities.

Ephedra intermedia  /  chemical constituents  /  β-hexosaminidase release rate
Xi-ling FAN, Yan-gang CAO, Xiao-ke ZHENG, Zhen-zhong WANG, Wei XIAO, Wei-sheng FENG. Chemical constituents of dichloromethane extract from the stems of Ephedra intermedia[J]. Acta Pharmaceutica Sinica, 2024 , 59 (9) : 2574 -2580 . DOI: 10.16438/j.0513-4870.2024-0168
Year 2024 volume 59 Issue 9
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doi: 10.16438/j.0513-4870.2024-0168
  • Receive Date:2024-02-27
  • Online Date:2025-11-24
  • Published:2024-09-12
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  • Received:2024-02-27
  • Revised:2024-04-30
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Affiliations
    1. Henan University of Chinese Medicine, Zhengzhou 450046, China
    2. Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou 450046, China
    3. Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan Province and Ministry of Education of China, Zhengzhou 450046, China
    4. State Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Lianyungang 222001, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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