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Discussion on the concerns in paediatric drug taste masking technology and evaluation
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Fang SHI, Lian-jie REN*
Acta Pharmaceutica Sinica | 2023, 58(11) : 3173 - 3178
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Acta Pharmaceutica Sinica | 2023, 58(11): 3173-3178
Special Reports: Pharmaceutical Taste-Masking and Assessment Technologies
Discussion on the concerns in paediatric drug taste masking technology and evaluation
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Fang SHI, Lian-jie REN*
Affiliations
  • Center for Drug Evaluation, National Medical Products Administration, Beijing 100076, China
Published: 2023-11-12 doi: 10.16438/j.0513-4870.2023-0861
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Good palatability of pediatric drugs improves the accuracy of dosing and adherence to dosing regimens. Many active pharmaceutical ingredients have an undesirable taste, so effective taste masking methods need to be developed to improve the palatability of pediatric medicines. This article mainly introduces the commonly taste masking techniques and taste evaluation methods, and puts forward suggestions on the concerns and general principles of the pharmaceutical evaluation of taste masking effects based on cases, in order to provide reference for the development of drug taste masking technology in children.

pediatric drug  /  taste masking  /  taste masking technique  /  taste evaluation
Fang SHI, Lian-jie REN. Discussion on the concerns in paediatric drug taste masking technology and evaluation[J]. Acta Pharmaceutica Sinica, 2023 , 58 (11) : 3173 -3178 . DOI: 10.16438/j.0513-4870.2023-0861
Year 2023 volume 58 Issue 11
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Article Info
doi: 10.16438/j.0513-4870.2023-0861
  • Receive Date:2023-07-13
  • Online Date:2025-11-21
  • Published:2023-11-12
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  • Received:2023-07-13
  • Revised:2023-09-20
Affiliations
    Center for Drug Evaluation, National Medical Products Administration, Beijing 100076, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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