Home Journals Articles Updates About
CN
image
收藏切换
Gut microbiota as a target for traditional Chinese medicine in the treatment of cardiovascular disease: potential mechanisms and therapy strategies
收藏切换
PDF
Wan-qi LE1, Jing-yu LIAO1, Yu-hao ZHANG1, 2, Gao-song WU1, *, Wei-dong ZHANG1, 2, 3, *
Acta Pharmaceutica Sinica | 2023, 58(8) : 1988 - 1999
Less
收藏切换
Acta Pharmaceutica Sinica | 2023, 58(8): 1988-1999
Gut microbiota as a target for traditional Chinese medicine in the treatment of cardiovascular disease: potential mechanisms and therapy strategies
Full
Wan-qi LE1, Jing-yu LIAO1, Yu-hao ZHANG1, 2, Gao-song WU1, *, Wei-dong ZHANG1, 2, 3, *
Affiliations
  • 1. Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
  • 2. School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China
  • 3. School of Pharmacy, Second Military Medical University, Shanghai 200433, China
Published: 2023-08-12 doi: 10.16438/j.0513-4870.2023-0261
Outline
收藏切换

Cardiovascular disease (CVD) is a major contributor to patient deaths worldwide, and its pathogenesis is complex and mortality rates are increasing every year. Numerous researches have shown that the gut microbiota and its metabolites were closely associated with the development of CVD, and gut microbiota was expected to be a potential new target for the treatment of CVD. Traditional Chinese medicine (TCM), characterized by its multi-component, multi-target and integrity, can play a therapeutic role in CVD by regulating the gut microbiota, which has obvious advantages in stabilizing the disease, improving heart function and enhancing quality of life, and is an ideal intestinal microecological regulator. Therefore, this review will mainly discuss the intimate association of gut microbiota and its metabolites with CVD, and the therapeutic strategies of TCM targeting gut microbiota to improve CVD, including regulating the composition of gut microbiota, protecting the intestinal mucosal barrier, influencing the intestinal immune function and modulating the metabolites of gut microbiota, in order to provide a reference for the research of TCM targeting gut microbiota for CVD.

gut microbiota  /  metabolite of gut microbiota  /  cardiovascular disease  /  traditional Chinese medicine  /  mechanism of action
Wan-qi LE, Jing-yu LIAO, Yu-hao ZHANG, Gao-song WU, Wei-dong ZHANG. Gut microbiota as a target for traditional Chinese medicine in the treatment of cardiovascular disease: potential mechanisms and therapy strategies[J]. Acta Pharmaceutica Sinica, 2023 , 58 (8) : 1988 -1999 . DOI: 10.16438/j.0513-4870.2023-0261
Appendix
Less
Year 2023 volume 58 Issue 8
PDF
200
81
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2023-0261
  • Receive Date：2023-03-05
  • Online Date：2025-11-21
  • Published：2023-08-12
Article Data
Affiliations
History
  • Received：2023-03-05
  • Revised：2023-03-20
Funding
Affiliations
    1. Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    2. School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China
    3. School of Pharmacy, Second Military Medical University, Shanghai 200433, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2023-0261
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House