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Application progress of electronic tongue on taste evaluation for drug products
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Shu-ye QI1, Li-hua GENG2, Yue ZHAO2, Chen WANG1, Li ZHU1, Shang-chen YAO1, Bao-ming NING1, *
Acta Pharmaceutica Sinica | 2023, 58(11) : 3151 - 3159
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Acta Pharmaceutica Sinica | 2023, 58(11): 3151-3159
Special Reports: Pharmaceutical Taste-Masking and Assessment Technologies
Application progress of electronic tongue on taste evaluation for drug products
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Shu-ye QI1, Li-hua GENG2, Yue ZHAO2, Chen WANG1, Li ZHU1, Shang-chen YAO1, Bao-ming NING1, *
Affiliations
  • 1. National Institutes for Food and Drug Control, Beijing 102629, China
  • 2. Ensoul Technology Ltd., Beijing 100055, China
Published: 2023-11-12 doi: 10.16438/j.0513-4870.2022-1413
Outline
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The taste of oral dosage forms has become a critical factor affecting the drug compliance and adherence to the treatment, and clinical application of the drug product may seriously restricted due to its bad taste. On the basis of the statement for the basic principle and specific performance of existing instruments, the application progress of electronic tongue on drug taste evaluation is addressed in detail. In view of its objective, fatigue-free, less harmful and accurate advantages, electronic tongue has been widely and meaningfully applied in the aspects of bitterness masking, and quality assessment and assurance of drug products. In addition, the reasons limiting the popularization of electronic tongue are mentioned in the paper, and some suggestions might be useful to enlarge the further application in the future.

electronic tongue  /  drug product  /  taste  /  taste masking  /  quality assessment
Shu-ye QI, Li-hua GENG, Yue ZHAO, Chen WANG, Li ZHU, Shang-chen YAO, Bao-ming NING. Application progress of electronic tongue on taste evaluation for drug products[J]. Acta Pharmaceutica Sinica, 2023 , 58 (11) : 3151 -3159 . DOI: 10.16438/j.0513-4870.2022-1413
Year 2023 volume 58 Issue 11
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Article Info
doi: 10.16438/j.0513-4870.2022-1413
  • Receive Date:2022-12-22
  • Online Date:2025-11-21
  • Published:2023-11-12
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History
  • Received:2022-12-22
  • Revised:2023-04-26
Funding
Affiliations
    1. National Institutes for Food and Drug Control, Beijing 102629, China
    2. Ensoul Technology Ltd., Beijing 100055, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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