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Progress on the neuroprotective effects of ginsenoside Rg1
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Jun-peng LONG1, 2, Yang SUN1, 2, Sha-sha LIU3, Jiao YAO1, 2, Song-wei YANG1, 2, Yan-tao YANG1, 2, Gang PEI1, 2, Lei MENG1, 2, Qi-di AI1, 2, *, Nai-hong CHEN1, 2, 4, *
Acta Pharmaceutica Sinica | 2023, 58(1) : 21 - 26
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Acta Pharmaceutica Sinica | 2023, 58(1): 21-26
• Reviews •
Progress on the neuroprotective effects of ginsenoside Rg1
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Jun-peng LONG1, 2, Yang SUN1, 2, Sha-sha LIU3, Jiao YAO1, 2, Song-wei YANG1, 2, Yan-tao YANG1, 2, Gang PEI1, 2, Lei MENG1, 2, Qi-di AI1, 2, *, Nai-hong CHEN1, 2, 4, *
Affiliations
  • 1. College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
  • 2. Hunan Engineering Technology Center of Standardization and Function of Chinese Herbal Decoction Pieces, Changsha 410208, China
  • 3. Xiangtan Central Hospital, Xiangtan 411199, China
  • 4. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2023-01-12 doi: 10.16438/j.0513-4870.2022-0740
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Ginsenoside Rg1 is one of the most important saponins in ginseng. It has a wide range of pharmacological activities. It is considered to be a powerful neuroprotective agent. It has neuroprotective effects such as anti-neuroinflammation, anti-oxidative stress, anti-neuronal apoptosis, and enhancing memory. Rg1 shows a good application prospect in the prevention and treatment of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, stroke, and mental diseases such as depression. This paper reviews the research on the neuroprotective mechanism of Rg1 at home and abroad in recent years, in order to provide new research ideas for the clinical treatment of nervous system diseases.

ginsenoside Rg1  /  neuroprotection  /  neurodegenerative disease  /  Alzheimer's disease  /  stroke
Jun-peng LONG, Yang SUN, Sha-sha LIU, Jiao YAO, Song-wei YANG, Yan-tao YANG, Gang PEI, Lei MENG, Qi-di AI, Nai-hong CHEN. Progress on the neuroprotective effects of ginsenoside Rg1[J]. Acta Pharmaceutica Sinica, 2023 , 58 (1) : 21 -26 . DOI: 10.16438/j.0513-4870.2022-0740
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doi: 10.16438/j.0513-4870.2022-0740
  • Receive Date：2022-06-16
  • Online Date：2025-11-21
  • Published：2023-01-12
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History
  • Received：2022-06-16
  • Revised：2022-07-14
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Affiliations
    1. College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
    2. Hunan Engineering Technology Center of Standardization and Function of Chinese Herbal Decoction Pieces, Changsha 410208, China
    3. Xiangtan Central Hospital, Xiangtan 411199, China
    4. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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