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Research progress of exosome delivery vehicles in tumor phototherapy
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Yu-liang YANG, Zhong-ming HUANG, Xi-liang LI, Yu LUO, Sheng-liang LI*
Acta Pharmaceutica Sinica | 2023, 58(3) : 506 - 515
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Acta Pharmaceutica Sinica | 2023, 58(3): 506-515
Research progress of exosome delivery vehicles in tumor phototherapy
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Yu-liang YANG, Zhong-ming HUANG, Xi-liang LI, Yu LUO, Sheng-liang LI*
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  • Soochow University, Suzhou 215123, China
Published: 2023-03-12 doi: 10.16438/j.0513-4870.2022-0736
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Exosome is a self-secreted phospholipid bilayer nanovesicles, and has shown great potential in drug delivery field due to the important advantages of low immunogenicity and homologous targeting. Phototherapy, mainly includes photodynamic therapy (PDT) and photothermal therapy (PTT), utilize light to activate photoactive drug for tumor cell killing. The advanced therapeutic strategy shows low toxic side-effect and non-invasion precise advantages, and thus has made great progress in tumor treatment over the past few years. Therefore, using exosomes as a drug delivery system to deliver phototherapeutic agents can improve therapeutic performances with a reduced side-effect, and further enhance their application potential for clinical tumor therapy. This review focus on the rising cross-subjects field involving exosomes and phototherapy, and mainly introduce the research progress and relative case of exosomes-based delivery system for cancer phototherapy. Additionally, the advantages and challenges of exosome-based phototherapy are also discussed and proposed.

exosome  /  delivery system  /  nanomedicine  /  neoplasm  /  photodynamic therapy  /  photothermal therapy
Yu-liang YANG, Zhong-ming HUANG, Xi-liang LI, Yu LUO, Sheng-liang LI. Research progress of exosome delivery vehicles in tumor phototherapy[J]. Acta Pharmaceutica Sinica, 2023 , 58 (3) : 506 -515 . DOI: 10.16438/j.0513-4870.2022-0736
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doi: 10.16438/j.0513-4870.2022-0736
  • Receive Date：2022-06-16
  • Online Date：2025-11-21
  • Published：2023-03-12
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  • Received：2022-06-16
  • Revised：2022-07-01
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    Soochow University, Suzhou 215123, China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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