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Research progress of metabolic flux analysis technology in glucose metabolism pathway research
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Yun-hao ZHAO1, Ting LINGHU1, Wen-ze WU1, Xian-xian WANG1, Yu-mei HAN2, Xue-mei QIN1, *, Jun-sheng TIAN1, *
Acta Pharmaceutica Sinica | 2022, 57(9) : 2731 - 2737
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Acta Pharmaceutica Sinica | 2022, 57(9): 2731-2737
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Research progress of metabolic flux analysis technology in glucose metabolism pathway research
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Yun-hao ZHAO1, Ting LINGHU1, Wen-ze WU1, Xian-xian WANG1, Yu-mei HAN2, Xue-mei QIN1, *, Jun-sheng TIAN1, *
Affiliations
  • 1. Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China
  • 2. School of Physical Education, Shanxi University, Taiyuan 030006, China
Published: 2022-09-12 doi: 10.16438/j.0513-4870.2022-0311
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With the wide application of stable isotope tracer metabolomics technology, its comprehensive analysis and in-depth mining of data are particularly important, and metabolic flux analysis is one of the main technical means, especially in the study of glucose metabolism. Metabolic flux analysis technology combines isotope tracing with mathematical models to deduce and calculate the metabolic flux between metabolites. The metabolic flux provides more information for research and reflects a dynamic metabolic process more clearly and specifically. This paper reviews the basic process, precautions, and application examples of metabolic flux analysis in glucose metabolism research, and provides a reference for the application of metabolic flux analysis based on stable isotope tracer metabolomics in glucose metabolism research.

metabolic flux analysis  /  stable isotope tracer metabolomics  /  glucose metabolism  /  metabolic pathway
Yun-hao ZHAO, Ting LINGHU, Wen-ze WU, Xian-xian WANG, Yu-mei HAN, Xue-mei QIN, Jun-sheng TIAN. Research progress of metabolic flux analysis technology in glucose metabolism pathway research[J]. Acta Pharmaceutica Sinica, 2022 , 57 (9) : 2731 -2737 . DOI: 10.16438/j.0513-4870.2022-0311
Year 2022 volume 57 Issue 9
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doi: 10.16438/j.0513-4870.2022-0311
  • Receive Date:2022-03-11
  • Online Date:2025-12-24
  • Published:2022-09-12
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  • Received:2022-03-11
  • Revised:2022-06-29
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    1. Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China
    2. School of Physical Education, Shanxi University, Taiyuan 030006, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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