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Bioinorganic chemistry strategies in antiviral drug discovery
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Shu-jing XU, Xu-jie ZHANG, Dang DING, Xin-yong LIU*, Peng ZHAN*
Acta Pharmaceutica Sinica | 2022, 57(3) : 576 - 592
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Acta Pharmaceutica Sinica | 2022, 57(3): 576-592
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Bioinorganic chemistry strategies in antiviral drug discovery
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Shu-jing XU, Xu-jie ZHANG, Dang DING, Xin-yong LIU*, Peng ZHAN*
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  • Department of Medicinal Chemistry, Key laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
Published: 2022-03-12 doi: 10.16438/j.0513-4870.2021-1132
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Over the course of human civilization, viral infections have been a part of human life and still represent one of the heaviest burdens for human and society, with a huge devastating socioeconomic impact. Inorganic and bioinorganic chemistry have made important contributions to medical science and human health in the past half century. In this paper, we selected the representative cases in recent years, and reviewed the research progress of antiviral drug discovery from the perspective of bioinorganic chemistry.

antiviral drug  /  bioinorganic chemistry  /  inhibitor  /  drug design  /  medicinal chemistry
Shu-jing XU, Xu-jie ZHANG, Dang DING, Xin-yong LIU, Peng ZHAN. Bioinorganic chemistry strategies in antiviral drug discovery[J]. Acta Pharmaceutica Sinica, 2022 , 57 (3) : 576 -592 . DOI: 10.16438/j.0513-4870.2021-1132
Year 2022 volume 57 Issue 3
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doi: 10.16438/j.0513-4870.2021-1132
  • Receive Date:2021-08-02
  • Online Date:2025-12-22
  • Published:2022-03-12
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  • Received:2021-08-02
  • Revised:2021-08-30
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    Department of Medicinal Chemistry, Key laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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