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Novel targets and strategies in antiviral drug discovery
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Shu-jing XU, Dang DING, Xu-jie ZHANG, Xin-yong LIU*, Peng ZHAN*
Acta Pharmaceutica Sinica | 2022, 57(4) : 903 - 916
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Acta Pharmaceutica Sinica | 2022, 57(4): 903-916
• Reviews •
Novel targets and strategies in antiviral drug discovery
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Shu-jing XU, Dang DING, Xu-jie ZHANG, Xin-yong LIU*, Peng ZHAN*
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  • Department of Medicinal Chemistry, Key laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
Published: 2022-04-12 doi: 10.16438/j.0513-4870.2021-1131
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Viral infections pose a persistent threat to human health and life. The rapid emergence of drug-resistant strains and the outbreak of new viruses require researchers to develop innovative strategies to accelerate the development of more antiviral drugs towards novel targets to meet the clinical needs. This paper selects typical research cases and reviews the novel targets and strategies of antiviral drugs in recent years from the perspective of medicinal chemistry.

antiviral drug  /  novel target  /  novel strategy  /  drug design
Shu-jing XU, Dang DING, Xu-jie ZHANG, Xin-yong LIU, Peng ZHAN. Novel targets and strategies in antiviral drug discovery[J]. Acta Pharmaceutica Sinica, 2022 , 57 (4) : 903 -916 . DOI: 10.16438/j.0513-4870.2021-1131
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Year 2022 volume 57 Issue 4
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Article Info
doi: 10.16438/j.0513-4870.2021-1131
  • Receive Date：2021-08-02
  • Online Date：2025-12-22
  • Published：2022-04-12
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History
  • Received：2021-08-02
  • Revised：2021-08-24
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Affiliations
    Department of Medicinal Chemistry, Key laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
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Genus		 种数
Number of
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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