Home Journals Articles Updates About
CN
image
收藏切换
Carrier-free nanoparticles based on self-assembly of active ingredients from Chinese medicine
收藏切换
PDF
Xing-xing FENG, Qi XIE, Cong-lian YANG, Li KONG*, Zhi-ping ZHANG*
Acta Pharmaceutica Sinica | 2021, 56(12) : 3203 - 3211
Less
收藏切换
Acta Pharmaceutica Sinica | 2021, 56(12): 3203-3211
• Special Reports Ⅰ: Anti-tumor Preparations of Traditional Chinese Medicine •
Carrier-free nanoparticles based on self-assembly of active ingredients from Chinese medicine
Full
Xing-xing FENG, Qi XIE, Cong-lian YANG, Li KONG*, Zhi-ping ZHANG*
Affiliations
  • Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China
Published: 2021-12-12 doi: 10.16438/j.0513-4870.2021-0748
Outline
收藏切换

Traditional Chinese medicine has a long history, unique system and perfect technology, which has been used to prevent or treat a variety of diseases in the form of compound medicine. Recently, some of the active ingredients from Chinese medicine were found to have self-assembly properties, mainly through non-covalent interactions, including π-π stacking, electrostatic interaction, hydrogen bond and coordination interactions, etc. Carrier-free nanoparticles based on self-assembly of active ingredients from Chinese medicine could not only improve the solubility of insoluble active ingredients, but also the bioavailability. As nanocarriers, the natural active ingredients could exert synergistic therapeutic effects. The strategy of self-assembly without carrier is safer and almost non-toxic compared to the commonly used nanocarriers. In addition, some ingredients from Chinese medicine could coordinate with metal ions to form stable nanoparticles, which could be applied to photothermal therapy. In this paper, we summarized and analyzed the recent achievements of carrier-free nanoparticles based on self-assembly of active ingredients from Chinese medicine, and briefly outlined the future development of this kind of nanomedicine.

Chinese medicine  /  natural product  /  self-assembly  /  nanoparticle
Xing-xing FENG, Qi XIE, Cong-lian YANG, Li KONG, Zhi-ping ZHANG. Carrier-free nanoparticles based on self-assembly of active ingredients from Chinese medicine[J]. Acta Pharmaceutica Sinica, 2021 , 56 (12) : 3203 -3211 . DOI: 10.16438/j.0513-4870.2021-0748
Appendix
Less
Year 2021 volume 56 Issue 12
PDF
216
93
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2021-0748
  • Receive Date：2021-05-18
  • Online Date：2025-12-18
  • Published：2021-12-12
Article Data
Affiliations
History
  • Received：2021-05-18
  • Revised：2021-06-16
Funding
Affiliations
    Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2021-0748
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House