Home Journals Articles Updates About
CN
image
收藏切换
Secondary metabolites of endophyte Alternaria sp. W-1 from Laminaria japonica
收藏切换
PDF
Sha-sha WANG1, 2, Xi CHEN3, Feng-wu WANG4, Ya-ping XU1, 2, Tong YE1, 2, Li SHEN1, 2, *
Acta Pharmaceutica Sinica | 2021, 56(8) : 2248 - 2251
Less
收藏切换
Acta Pharmaceutica Sinica | 2021, 56(8): 2248-2251
• Original Articles •
Secondary metabolites of endophyte Alternaria sp. W-1 from Laminaria japonica
Full
Sha-sha WANG1, 2, Xi CHEN3, Feng-wu WANG4, Ya-ping XU1, 2, Tong YE1, 2, Li SHEN1, 2, *
Affiliations
  • 1. Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, China
  • 2. Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou 225001, China
  • 3. Yangzhou Hospital of TCM, Yangzhou 225001, China
  • 4. College of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China
Published: 2021-08-12 doi: 10.16438/j.0513-4870.2021-0488
Outline
收藏切换

Six compounds were isolated from the crude extract of the liquid culture of Alternaria sp. W-1 by silica gel column chromatography, Sephadex LH-20 gel column chromatography, and HPLC. They were identified as 6-iso-tricycloalternarene 6a (1), tricycloalternarene 6a (2), tricycloalternarene B (3), uracil (4), 5-methyluracil (5), and lumichrome (6) through HR-MS, NMR and literature comparison. 6-iso-Tricycloalternarene 6a (1) is a new compound which has never been reported in the literature. In cytotoxicity assay, compounds 1-3 showed weak inhibition activity to human hepatoma cell line SMMC-7721 and human gastric cell line SGC-7901.

Laminaria japonica  /  endophyte  /  Alternaria sp.  /  secondary metabolite  /  tricycloalternarene compound
Sha-sha WANG, Xi CHEN, Feng-wu WANG, Ya-ping XU, Tong YE, Li SHEN. Secondary metabolites of endophyte Alternaria sp. W-1 from Laminaria japonica[J]. Acta Pharmaceutica Sinica, 2021 , 56 (8) : 2248 -2251 . DOI: 10.16438/j.0513-4870.2021-0488
Appendix
Less
Year 2021 volume 56 Issue 8
PDF
153
68
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2021-0488
  • Receive Date：2021-04-06
  • Online Date：2025-12-18
  • Published：2021-08-12
Article Data
Affiliations
History
  • Received：2021-04-06
  • Revised：2021-04-28
Funding
Affiliations
    1. Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, China
    2. Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou 225001, China
    3. Yangzhou Hospital of TCM, Yangzhou 225001, China
    4. College of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2021-0488
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House