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Research progress of tumor imaging agents targeting mannose receptor
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Dan WU1, 2, Cong CHEN3, Chang-hao LIU1, 2, Hong-liang WEN*, 1, 2
Acta Pharmaceutica Sinica | 2021, 56(10) : 2769 - 2778
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Acta Pharmaceutica Sinica | 2021, 56(10): 2769-2778
• Reviews •
Research progress of tumor imaging agents targeting mannose receptor
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Dan WU1, 2, Cong CHEN3, Chang-hao LIU1, 2, Hong-liang WEN*, 1, 2
Affiliations
  • 1. School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 102488, China
  • 2. Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, Beijing 102488, China
  • 3. School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Benxi 117000, China
Published: 2021-10-12 doi: 10.16438/j.0513-4870.2021-0386
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Cancer is a malignant disease threatening human health and life. Early diagnosis of carcinoma plays an important role in the treatment of carcinoma, so tumor imaging agents have been the focus of research in this field. Mannose receptor is a C-type lectin receptor, which expressed in various tumor tissues, sentinel lymph nodes and has become an important tumor marker. In recent years, a variety of imaging agents targeting mannose receptors have been designed and developed. This review summarizes the representative achievements.

tumor  /  mannose receptor  /  targeting  /  imaging agent  /  diagnosis
Dan WU, Cong CHEN, Chang-hao LIU, Hong-liang WEN. Research progress of tumor imaging agents targeting mannose receptor[J]. Acta Pharmaceutica Sinica, 2021 , 56 (10) : 2769 -2778 . DOI: 10.16438/j.0513-4870.2021-0386
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Article Info
doi: 10.16438/j.0513-4870.2021-0386
  • Receive Date：2021-03-18
  • Online Date：2025-12-18
  • Published：2021-10-12
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History
  • Received：2021-03-18
  • Revised：2021-04-26
Affiliations
    1. School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 102488, China
    2. Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, Beijing 102488, China
    3. School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Benxi 117000, China
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多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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