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Clinical and pharmacological research progress of Tibetan medicine in prevention and treatment for hepatic fibrosis
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Pu-yang GONG1, Ke-huan YIN1, Xue-dong LI1, Jian GU1, *, Rui TAN2
Acta Pharmaceutica Sinica | 2021, 56(11) : 2995 - 3003
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Acta Pharmaceutica Sinica | 2021, 56(11): 2995-3003
• Reviews •
Clinical and pharmacological research progress of Tibetan medicine in prevention and treatment for hepatic fibrosis
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Pu-yang GONG1, Ke-huan YIN1, Xue-dong LI1, Jian GU1, *, Rui TAN2
Affiliations
  • 1. College of Pharmacy, Southwest Minzu University, Chengdu 610041, China
  • 2. College of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China
Published: 2021-11-12 doi: 10.16438/j.0513-4870.2021-0264
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Hepatic fibrosis is a common pathological link of multiple chronic liver diseases, and further causes cirrhosis and even liver cancer. Tibetan medicine possessed significant and unique clinical effects in the prevention and treatment of hepatic fibrosis through unique medication methods such as single prescription, time synergy, and dialectical combination prescription. Pharmacological experimental studies have shown that a variety of Tibetan medicine formulas and herbs have anti-fibrotic effects, and their main pharmacological action mechanism involves inhibiting lipid peroxidation, reducing liver stellate cell activation and proliferation, regulating collagen metabolism, etc. This review summarizes the research progress of the clinical application and pharmacodynamic mechanism of Tibetan medicine in the prevention and treatment of liver fibrosis, aiming to provide a reference for the development of clinical use and innovative drugs discovery of Tibetan medicine against hepatic fibrosis.

Tibetan medicine  /  hepatic fibrosis  /  clinical application  /  pharmacological mechanism  /  drug development
Pu-yang GONG, Ke-huan YIN, Xue-dong LI, Jian GU, Rui TAN. Clinical and pharmacological research progress of Tibetan medicine in prevention and treatment for hepatic fibrosis[J]. Acta Pharmaceutica Sinica, 2021 , 56 (11) : 2995 -3003 . DOI: 10.16438/j.0513-4870.2021-0264
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Article Info
doi: 10.16438/j.0513-4870.2021-0264
  • Receive Date：2021-02-23
  • Online Date：2025-12-18
  • Published：2021-11-12
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History
  • Received：2021-02-23
  • Revised：2021-03-28
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    1. College of Pharmacy, Southwest Minzu University, Chengdu 610041, China
    2. College of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China
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表12种不同金属材料的力学参数
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Number of
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Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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