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Research progress of antioxidant drugs in myocardial ischemia-reperfusion injury
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Jing-wen XIE1, 2, Tian-de SU2, Yu-ting WEI1, Ge LI2, Jian-zhang WU2, *, Li-li HUANG3, *
Acta Pharmaceutica Sinica | 2021, 56(7) : 1845 - 1855
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Acta Pharmaceutica Sinica | 2021, 56(7): 1845-1855
• Reviews •
Research progress of antioxidant drugs in myocardial ischemia-reperfusion injury
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Jing-wen XIE1, 2, Tian-de SU2, Yu-ting WEI1, Ge LI2, Jian-zhang WU2, *, Li-li HUANG3, *
Affiliations
  • 1. Department of Pharmacy, the First People's Hospital of Wanzhou District, Chongqing 404040, China
  • 2. School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China
  • 3. Department of Pharmacy, Lihuili Hospital Affiliated to Ningbo University, Ningbo 315040, China
Published: 2021-07-12 doi: 10.16438/j.0513-4870.2020-1988
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Myocardial ischemia-reperfusion injury (MIRI) is one of the most difficulties in the studies of cardiovascular diseases, and excessive reactive oxygen species (ROS) accumulation in cells is the main cause of it. Reducing ROS level by antioxidant drugs to protect cardiomyocytes is being the spotlight on MIRI treatment. In this review, the research progress of antioxidant drugs in myocardial ischemia-reperfusion injury in recent years was summarized.

myocardial ischemia-reperfusion injury  /  antioxidant  /  free radical  /  oxidative stress  /  mechanism
Jing-wen XIE, Tian-de SU, Yu-ting WEI, Ge LI, Jian-zhang WU, Li-li HUANG. Research progress of antioxidant drugs in myocardial ischemia-reperfusion injury[J]. Acta Pharmaceutica Sinica, 2021 , 56 (7) : 1845 -1855 . DOI: 10.16438/j.0513-4870.2020-1988
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Article Info
doi: 10.16438/j.0513-4870.2020-1988
  • Receive Date：2020-12-30
  • Online Date：2025-12-18
  • Published：2021-07-12
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History
  • Received：2020-12-30
  • Revised：2021-01-28
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Affiliations
    1. Department of Pharmacy, the First People's Hospital of Wanzhou District, Chongqing 404040, China
    2. School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China
    3. Department of Pharmacy, Lihuili Hospital Affiliated to Ningbo University, Ningbo 315040, China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
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Number of
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Percentage of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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