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The latest research progress of torpor occurrence mechanism
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Zi-yu ZHU, Jian-wei JIANG, Jian-jun* ZHANG*
Acta Pharmaceutica Sinica | 2021, 56(6) : 1532 - 1536
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Acta Pharmaceutica Sinica | 2021, 56(6): 1532-1536
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The latest research progress of torpor occurrence mechanism
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Zi-yu ZHU, Jian-wei JIANG, Jian-jun* ZHANG*
Affiliations
  • Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2021-06-12 doi: 10.16438/j.0513-4870.2020-1751
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Torpor refers to a state in which the metabolic activity in the body of the living animal is greatly reduced during the period of reduced food supply, which is manifested as a substantial decrease in body temperature, metabolic level, and exercise level. Mammals have a strict body temperature regulation system to maintain a constant body temperature. When the energy supply is insufficient for a long time, some mammals will enter a hibernation state. Torpor is very similar to the hibernation state. The research on the mechanism of torpor state is of great significance in aerospace, military medicine and other fields. This review summarizes the specific mechanisms regulating the occurrence of torpor from four aspects: adenylate cyclase activating polypeptide (adcyap) neurons, leptin, pyroglutamylated RFamide peptide (QRFP) neurons, and sympathetic nervous system, aiming to provide ideas for further research on the mechanism of torpor.

torpor  /  adcyap neuron  /  leptin  /  QRFP neuron  /  sympathetic nervous system
Zi-yu ZHU, Jian-wei JIANG, Jian-jun* ZHANG. The latest research progress of torpor occurrence mechanism[J]. Acta Pharmaceutica Sinica, 2021 , 56 (6) : 1532 -1536 . DOI: 10.16438/j.0513-4870.2020-1751
Year 2021 volume 56 Issue 6
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Article Info
doi: 10.16438/j.0513-4870.2020-1751
  • Receive Date:2020-11-11
  • Online Date:2025-12-18
  • Published:2021-06-12
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  • Received:2020-11-11
  • Revised:2021-01-19
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    Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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