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Research advances on the chemical components and pharmacological activities of Zanthoxyli Radix
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Jia-li FU, Lu-ming YANG, Xin-yue FAN, Qiao-ru GUO, Wen-min ZHOU, Jian-ye ZHANG*
Acta Pharmaceutica Sinica | 2021, 56(8) : 2169 - 2181
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Acta Pharmaceutica Sinica | 2021, 56(8): 2169-2181
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Research advances on the chemical components and pharmacological activities of Zanthoxyli Radix
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Jia-li FU, Lu-ming YANG, Xin-yue FAN, Qiao-ru GUO, Wen-min ZHOU, Jian-ye ZHANG*
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  • Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, China
Published: 2021-08-12 doi: 10.16438/j.0513-4870.2020-1718
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Zanthoxyli Radix is a traditional Chinese medicine. It can be used for the treatment of wind-colddampness arthralgia, muscle and bone pain, fall fracture, hernia, sore throat, toothache and other diseases. Due to possessing many excellent and mild pharmacological properties, there are lots of reports about Zanthoxyli Radix worldwide. At present, more than 100 bioactive components have been extracted and purified from Zanthoxyli Radix. Nitidine chloride (NC), one of the most important alkaloids in Zanthoxyli Radix, has the activities of antitumor, anti-inflammation, anti-bacteria, etc. In this review, we summarize the chemical components of Zanthoxyli Radix, pharmacological activity and mechanism of action of NC to provide references for further research and utilization of Zanthoxyli Radix.

Zanthoxyli Radix  /  nitidine chloride  /  component  /  pharmacological activity  /  mechanism
Jia-li FU, Lu-ming YANG, Xin-yue FAN, Qiao-ru GUO, Wen-min ZHOU, Jian-ye ZHANG. Research advances on the chemical components and pharmacological activities of Zanthoxyli Radix[J]. Acta Pharmaceutica Sinica, 2021 , 56 (8) : 2169 -2181 . DOI: 10.16438/j.0513-4870.2020-1718
Year 2021 volume 56 Issue 8
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doi: 10.16438/j.0513-4870.2020-1718
  • Receive Date:2020-11-09
  • Online Date:2025-12-18
  • Published:2021-08-12
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  • Received:2020-11-09
  • Revised:2020-12-02
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    Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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